Biomarkers of cell cycle arrest, microcirculation dysfunction, and inflammation in the prediction of SA-AKI

Biomarkers of cell cycle arrest, microcirculation dysfunction, and inflammation in the prediction of SA-AKI

Abstract Sepsis-associated acute kidney injury (SA-AKI) is a severe complication in critically ill patients, with a complex pathogenesis involving in cell cycle arrest, microcirculatory dysfunction, and inflammation. Current diagnostic strategies remain suboptimal. Therefore, this study aimed to eva...

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Bibliographic Details
Main Authors: Qian Zhang, Boxin Yang, Xiaodan Li, Yang Zhao, Shuo Yang, Qingbian Ma, Liyan Cui
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Sepsis associated acute kidney injury
Biomarkers
Tissue inhibitor metalloproteinase-2
Insulin-like growth factor-binding protein-7
Angiopoeitin-2
Procalcitonin
Online Access:https://doi.org/10.1038/s41598-025-92315-y
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