A nanoparticle loaded nasal sol-gel system of midazolam hydrochloride for the management of intermittent seizures

A nanoparticle loaded nasal sol-gel system of midazolam hydrochloride for the management of intermittent seizures

Objective(s): Midazolam hydrochloride is a short-acting hypnotic sedative with anticonvulsant properties. Considering the poor bioavailability, rapid elimination, and inconvenience of administering oral medication in epileptic conditions, this study proposed the use of a nanoparticulate in situ nasa...

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Bibliographic Details
Main Authors: Venkatesh Srinivasan, Preethi Sudheer, Keserla Bhavani, Arumugam Muthu Kumar
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-07-01
Series:Nanomedicine Journal
Subjects:
nasal ,gellan gum
midazolam
nanoparticles
plga
Online Access:https://nmj.mums.ac.ir/article_25804_050c24598acadbf2308cee64ac3c6d44.pdf
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