Hepatorenal Syndrome with Cirrhotic Cardiomyopathy: Case Report and Literature Review

The hepatorenal syndrome (HRS) is defined as a potentially reversible kidney failure in patients with cirrhosis and ascites. An association of HRS and cirrhotic cardiomyopathy has been reported recently, but there are no result studies about the use of positive inotropes as part of the acute phase t...

Full description

Saved in:
Bibliographic Details
Main Authors: Luis Mocarzel, Pedro Lanzieri, Juliana Nascimento, Clara Peixoto, Mário Ribeiro, Evandro Mesquita
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Hepatology
Online Access:http://dx.doi.org/10.1155/2015/573513
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The hepatorenal syndrome (HRS) is defined as a potentially reversible kidney failure in patients with cirrhosis and ascites. An association of HRS and cirrhotic cardiomyopathy has been reported recently, but there are no result studies about the use of positive inotropes as part of the acute phase treatment. We report the case of a patient diagnosed with HRS, with high levels of NT pro-BNP, but with normal ejection fraction of the left ventricle, which showed abnormalities in systolic function through speckle tracking in echocardiography, reversible after the infusion of dobutamine. The patient showed clinical and laboratory improvement of his renal function after the infusion of dobutamine. Clinical studies are needed on HRS therapeutic approach taking into account the myocardial dysfunction as a major contributing factor to renal dysfunction.
ISSN:2090-6587
2090-6595