Nuclear factor-kappa B and diabetic nephropathy
Diabetes is a metabolic disease that affects most of the world’s population. Diabetic nephropathy(DN) is the main complication of diabetes mellitus and the main cause of end-stage renal diseases. At present, the pathogenesis of diabetic nephropathy is not completely clear. Studies have shown that NF...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2019-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57911653&Fpath=home&index=0 |
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| Summary: | Diabetes is a metabolic disease that affects most of the world’s population. Diabetic nephropathy(DN) is the main complication of diabetes mellitus and the main cause of end-stage renal diseases. At present, the pathogenesis of diabetic nephropathy is not completely clear. Studies have shown that NF-kappa B plays an important role in the pathogenesis of diabetic nephropathy. Studying various natural and synthetic inhibitors of NF-kappa B is helpful to the treatment and management of DN. This article reviews the role of NF-kappa B in the pathogenesis of diabetic nephropathy and the research progress. |
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| ISSN: | 1671-2390 |