Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
We report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceft...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-01-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2020.1732836 |
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| author | Shao-Chun Chen Li-Hua Hu Xiao-Yu Zhu Yue-Ping Yin |
| author_facet | Shao-Chun Chen Li-Hua Hu Xiao-Yu Zhu Yue-Ping Yin |
| author_sort | Shao-Chun Chen |
| collection | DOAJ |
| description | We report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceftriaxone. The SPC high-level resistance (MIC = 2048 mg/L) was due to a small deletion in rspE that caused two amino acid changes in ribosomal protein S5. |
| format | Article |
| id | doaj-art-30cc172b92fa46e9bf62ca78ee2e938f |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-30cc172b92fa46e9bf62ca78ee2e938f2025-08-20T02:26:36ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512020-01-019151751910.1080/22221751.2020.1732836Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in ChinaShao-Chun Chen0Li-Hua Hu1Xiao-Yu Zhu2Yue-Ping Yin3Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, People’s Republic of ChinaZhejiang Provincial Institute of Dermatology, Deqing, People’s Republic of ChinaInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, People’s Republic of ChinaInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, People’s Republic of ChinaWe report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceftriaxone. The SPC high-level resistance (MIC = 2048 mg/L) was due to a small deletion in rspE that caused two amino acid changes in ribosomal protein S5.https://www.tandfonline.com/doi/10.1080/22221751.2020.1732836Neisseria gonorrhoeaespectinomycinresistanceurethritistreatment failure |
| spellingShingle | Shao-Chun Chen Li-Hua Hu Xiao-Yu Zhu Yue-Ping Yin Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China Emerging Microbes and Infections Neisseria gonorrhoeae spectinomycin resistance urethritis treatment failure |
| title | Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China |
| title_full | Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China |
| title_fullStr | Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China |
| title_full_unstemmed | Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China |
| title_short | Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China |
| title_sort | gonococcal urethritis caused by a multidrug resistant neisseria gonorrhoeae strain with high level resistance to spectinomycin in china |
| topic | Neisseria gonorrhoeae spectinomycin resistance urethritis treatment failure |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2020.1732836 |
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