Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration

It has been shown that stem cell transplantation can regenerate periodontal tissue, and several clinical trials involving transplantation of stem cells into human patients have already begun or are in preparation. However, stem cell transplantation therapy is a new technology, and the events followi...

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Main Authors: Toshiyuki Yoshida, Kaoru Washio, Takanori Iwata, Teruo Okano, Isao Ishikawa
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2012/307024
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author Toshiyuki Yoshida
Kaoru Washio
Takanori Iwata
Teruo Okano
Isao Ishikawa
author_facet Toshiyuki Yoshida
Kaoru Washio
Takanori Iwata
Teruo Okano
Isao Ishikawa
author_sort Toshiyuki Yoshida
collection DOAJ
description It has been shown that stem cell transplantation can regenerate periodontal tissue, and several clinical trials involving transplantation of stem cells into human patients have already begun or are in preparation. However, stem cell transplantation therapy is a new technology, and the events following transplantation are poorly understood. Several studies have reported side effects and potential risks associated with stem cell transplantation therapy. To protect patients from such risks, governments have placed regulations on stem cell transplantation therapies. It is important for the clinicians to understand the relevant risks and governmental regulations. This paper describes the ongoing clinical studies, basic research, risks, and governmental controls related to stem cell transplantation therapy. Then, one clinical study is introduced as an example of a government-approved periodontal cell transplantation therapy.
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institution OA Journals
issn 1687-8728
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publishDate 2012-01-01
publisher Wiley
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series International Journal of Dentistry
spelling doaj-art-30c5c604d1434ba18feaf67cd61e38472025-08-20T02:38:57ZengWileyInternational Journal of Dentistry1687-87281687-87362012-01-01201210.1155/2012/307024307024Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue RegenerationToshiyuki Yoshida0Kaoru Washio1Takanori Iwata2Teruo Okano3Isao Ishikawa4Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawata-cho, Shinjuku-ku, Tokyo 162-8666, JapanInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawata-cho, Shinjuku-ku, Tokyo 162-8666, JapanInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawata-cho, Shinjuku-ku, Tokyo 162-8666, JapanInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawata-cho, Shinjuku-ku, Tokyo 162-8666, JapanInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawata-cho, Shinjuku-ku, Tokyo 162-8666, JapanIt has been shown that stem cell transplantation can regenerate periodontal tissue, and several clinical trials involving transplantation of stem cells into human patients have already begun or are in preparation. However, stem cell transplantation therapy is a new technology, and the events following transplantation are poorly understood. Several studies have reported side effects and potential risks associated with stem cell transplantation therapy. To protect patients from such risks, governments have placed regulations on stem cell transplantation therapies. It is important for the clinicians to understand the relevant risks and governmental regulations. This paper describes the ongoing clinical studies, basic research, risks, and governmental controls related to stem cell transplantation therapy. Then, one clinical study is introduced as an example of a government-approved periodontal cell transplantation therapy.http://dx.doi.org/10.1155/2012/307024
spellingShingle Toshiyuki Yoshida
Kaoru Washio
Takanori Iwata
Teruo Okano
Isao Ishikawa
Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration
International Journal of Dentistry
title Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration
title_full Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration
title_fullStr Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration
title_full_unstemmed Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration
title_short Current Status and Future Development of Cell Transplantation Therapy for Periodontal Tissue Regeneration
title_sort current status and future development of cell transplantation therapy for periodontal tissue regeneration
url http://dx.doi.org/10.1155/2012/307024
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