MED13‐dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver

MED13‐dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver

Abstract The heart requires a continuous supply of energy but has little capacity for energy storage and thus relies on exogenous metabolic sources. We previously showed that cardiac MED13 modulates systemic energy homeostasis in mice. Here, we sought to define the extra‐cardiac tissue(s) that respo...

Full description

Saved in:
Bibliographic Details
Main Authors: Kedryn K Baskin, Chad E Grueter, Christine M Kusminski, William L Holland, Angie L Bookout, Santosh Satapati, Y Megan Kong, Shawn C Burgess, Craig R Malloy, Philipp E Scherer, Christopher B Newgard, Rhonda Bassel‐Duby, Eric N Olson
Format: Article
Language:English
Published: Springer Nature 2014-11-01
Series:EMBO Molecular Medicine
Subjects:
energy homeostasis
mediator complex
metabolic flexibility
metabolic gene expression
metabolism
Online Access:https://doi.org/10.15252/emmm.201404218
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items