The gut microbiota protein BOC1 exhibits immune checkpoint inhibitor-like activity by inhibiting myeloid-derived suppressor cell differentiation

The gut microbiota protein BOC1 exhibits immune checkpoint inhibitor-like activity by inhibiting myeloid-derived suppressor cell differentiation

BackgroundAdvancing research in oncology highlights the inverse correlation between antibiotic treatment and the positive outcomes of immune checkpoint inhibitor (ICI) administration, confirming once more the importance of microbiota and microbiota-derived compounds as complementary tools for treati...

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Bibliographic Details
Main Authors: Laureen Bardouillet, Maria Lucia Orsini Delgado, Caroline Matondo, Francesco Strozzi, Valentine Thomas, Laurent Chene, Antonietta Cultrone
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
gut microbiota
immune check-point inhibitor
CD200R1
MDSC
cancer immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1607543/full
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