Trans-cinnamaldehyde ameliorates neuroinflammation-mediated synaptic plasticity and memory impairment by blocking TLR4/MyD88/MAPKs pathway in global cerebral ischemia
Global cerebral ischemia (GCI), a severe form of ischemic stroke, leads to significant cognitive and neurological deficits, with neuroinflammation playing a central role in its pathophysiology. Trans-cinnamaldehyde (TCA), derived from Cinnamomum cassia (L.), has demonstrated anti-inflammatory and ne...
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| Main Authors: | Xinjuan Liu, Zhiyuan Lu, Gaiying He, Waimao Gao, Kaifan Hu, Jie Pan, Yan Zhao, Xingyu Wang, Guang Yang, Ying Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Brain Research Bulletin |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923025002680 |
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