An immunoinformatics and extensive molecular dynamics study to develop a polyvalent multi-epitope vaccine against cryptococcosis.

An immunoinformatics and extensive molecular dynamics study to develop a polyvalent multi-epitope vaccine against cryptococcosis.

Cryptococcosis is a lethal mycosis instigated by the pathogenic species Cryptococcus neoformans and Cryptococcus gattii, primarily affects the lungs, manifesting as pneumonia, and the brain, where it presents as meningitis. Mortality rate could reach 100% if infections remain untreated in cryptococc...

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Main Authors: Md Razwan Sardar Sami, Nurul Amin Rani, Mohammad Mahfuz Enam Elahi, Mohammad Sajjad Hossain, Minhaz Abdullah Al Mueid, Zahidur Rahim, Rajesh B Patil, Abu Tayab Moin, Israt Jahan Bithi, Sabekun Nahar, Israt Jahan Konika, Sneha Roy, Jannatul Aleya Preya, Jamil Ahmed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0315105
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