Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries
Abstract Cancer is a major global health challenge, with approximately 19.3 million new cases and 10 million deaths estimated by 2020. Laboratory advancements in cancer detection have transformed diagnostic capabilities, particularly through the use of biomarkers that play crucial roles in risk asse...
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| Format: | Article |
| Language: | English |
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Springer
2025-02-01
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| Series: | Discover Oncology |
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| Online Access: | https://doi.org/10.1007/s12672-025-01877-w |
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| author | Azeez Okikiola Lawal Tolutope Joseph Ogunniyi Oriire Idunnuoluwa Oludele Oluwaloseyi Ayomipo Olorunfemi Olalekan John Okesanya Jerico Bautista Ogaya Emery Manirambona Mohamed Mustaf Ahmed Don Eliseo Lucero-Prisno |
| author_facet | Azeez Okikiola Lawal Tolutope Joseph Ogunniyi Oriire Idunnuoluwa Oludele Oluwaloseyi Ayomipo Olorunfemi Olalekan John Okesanya Jerico Bautista Ogaya Emery Manirambona Mohamed Mustaf Ahmed Don Eliseo Lucero-Prisno |
| author_sort | Azeez Okikiola Lawal |
| collection | DOAJ |
| description | Abstract Cancer is a major global health challenge, with approximately 19.3 million new cases and 10 million deaths estimated by 2020. Laboratory advancements in cancer detection have transformed diagnostic capabilities, particularly through the use of biomarkers that play crucial roles in risk assessment, therapy selection, and disease monitoring. Tumor histology, single-cell technology, flow cytometry, molecular imaging, liquid biopsy, immunoassays, and molecular diagnostics have emerged as pivotal tools for cancer detection. The integration of artificial intelligence, particularly deep learning and convolutional neural networks, has enhanced the diagnostic accuracy and data analysis capabilities. However, developing countries face significant challenges including financial constraints, inadequate healthcare infrastructure, and limited access to advanced diagnostic technologies. The impact of COVID-19 has further complicated cancer management in resource-limited settings. Future research should focus on precision medicine and early cancer diagnosis through sophisticated laboratory techniques to improve prognosis and health outcomes. This review examines the evolving landscape of cancer detection, focusing on laboratory research breakthroughs and limitations in developing countries, while providing recommendations for advancing tumor diagnostics in resource-constrained environments. |
| format | Article |
| id | doaj-art-30a4e629de57464186c197418c53528b |
| institution | Kabale University |
| issn | 2730-6011 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Oncology |
| spelling | doaj-art-30a4e629de57464186c197418c53528b2025-02-09T12:43:19ZengSpringerDiscover Oncology2730-60112025-02-0116111410.1007/s12672-025-01877-wInnovative laboratory techniques shaping cancer diagnosis and treatment in developing countriesAzeez Okikiola Lawal0Tolutope Joseph Ogunniyi1Oriire Idunnuoluwa Oludele2Oluwaloseyi Ayomipo Olorunfemi3Olalekan John Okesanya4Jerico Bautista Ogaya5Emery Manirambona6Mohamed Mustaf Ahmed7Don Eliseo Lucero-Prisno8Department of Medical Laboratory Science, Kwara State UniversityDepartment of Medical Laboratory Science, Kwara State UniversityDepartment of Medical Laboratory Science, University Teaching HospitalDepartment of Medical Laboratory Science, University of Ilorin Teaching HospitalDepartment of Public Health and Maritime Transport, University of ThessalyDepartment of Medical Technology, Institute of Health Sciences and Nursing, Far Eastern UniversityDepartment of Medicine, University of RwandaFaculty of Medicine and Health Sciences, SIMAD UniversityDepartment of Global Health and Development, London School of Hygiene and Tropical MedicineAbstract Cancer is a major global health challenge, with approximately 19.3 million new cases and 10 million deaths estimated by 2020. Laboratory advancements in cancer detection have transformed diagnostic capabilities, particularly through the use of biomarkers that play crucial roles in risk assessment, therapy selection, and disease monitoring. Tumor histology, single-cell technology, flow cytometry, molecular imaging, liquid biopsy, immunoassays, and molecular diagnostics have emerged as pivotal tools for cancer detection. The integration of artificial intelligence, particularly deep learning and convolutional neural networks, has enhanced the diagnostic accuracy and data analysis capabilities. However, developing countries face significant challenges including financial constraints, inadequate healthcare infrastructure, and limited access to advanced diagnostic technologies. The impact of COVID-19 has further complicated cancer management in resource-limited settings. Future research should focus on precision medicine and early cancer diagnosis through sophisticated laboratory techniques to improve prognosis and health outcomes. This review examines the evolving landscape of cancer detection, focusing on laboratory research breakthroughs and limitations in developing countries, while providing recommendations for advancing tumor diagnostics in resource-constrained environments.https://doi.org/10.1007/s12672-025-01877-wCancerCancer diagnosisLaboratory investigationTumor researchBiomarkersLaboratory challenges |
| spellingShingle | Azeez Okikiola Lawal Tolutope Joseph Ogunniyi Oriire Idunnuoluwa Oludele Oluwaloseyi Ayomipo Olorunfemi Olalekan John Okesanya Jerico Bautista Ogaya Emery Manirambona Mohamed Mustaf Ahmed Don Eliseo Lucero-Prisno Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries Discover Oncology Cancer Cancer diagnosis Laboratory investigation Tumor research Biomarkers Laboratory challenges |
| title | Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries |
| title_full | Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries |
| title_fullStr | Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries |
| title_full_unstemmed | Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries |
| title_short | Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries |
| title_sort | innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries |
| topic | Cancer Cancer diagnosis Laboratory investigation Tumor research Biomarkers Laboratory challenges |
| url | https://doi.org/10.1007/s12672-025-01877-w |
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