The alterations of molecular repertoire of the RANKL-induced osteoclastogenesis in the M1 macrophage-derived inflammatory milieu
Abstract Inflammation have been linked to bone diseases such as osteoporosis or bone destruction. However, whether M1 inflammatory stimuli exert a stimulatory or inhibitory effect on the differentiation of osteoclasts remained controversial. Also, how inflammatory milieu influence cell proliferation...
Saved in:
| Main Authors: | Chun-Shan Wu, Ching-Yun Chen, Chin-Hua Yang, Yu-Pao Hsu, Ching-Hsiao Yu, Yu-Hsu Chen, Shau-Kwaun Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-99772-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
One arrow two eagles: Multifunctional nano-system for macrophage reprogramming and osteoclastogenesis inhibition against inflammatory osteolysis
by: Tong Sha, et al.
Published: (2024-12-01) -
Leptin Promotes the Expression of Pro-inflammatory Mediator Genes but Does Not Alter Osteoclastogenesis and Early Stage Differentiation of Osteoblasts
by: Chien-Ning Hsu, et al.
Published: (2024-12-01) -
Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome
by: Wei Zhang, et al.
Published: (2025-08-01) -
The unexplored relationship between spontaneous osteoclastogenesis and platelets in osteoporosis
by: Francesca Salamanna, et al.
Published: (2025-07-01) -
Effect of lincRNA-EPS on osteoclastogenesis of RAW264.7 cells induced by RANKL and LPS: An experimental study
by: ZHANG Xu, et al.
Published: (2024-06-01)