Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV
We conducted cross-sectional, multicenter studies in HIV-positive young women and men to assess metabolic and morphologic complications from tobacco smoking in 372 behaviorally infected HIV-positive youth, aged 14–25 years. Measurements included self-reported tobacco use, fasting lipids, glucose, fa...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | AIDS Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2014/740545 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832549085426483200 |
|---|---|
| author | Mark L. Rubinstein D. Robert Harris Bret J. Rudy Bill G. Kapogiannis Grace M. Aldrovandi Kathleen Mulligan |
| author_facet | Mark L. Rubinstein D. Robert Harris Bret J. Rudy Bill G. Kapogiannis Grace M. Aldrovandi Kathleen Mulligan |
| author_sort | Mark L. Rubinstein |
| collection | DOAJ |
| description | We conducted cross-sectional, multicenter studies in HIV-positive young women and men to assess metabolic and morphologic complications from tobacco smoking in 372 behaviorally infected HIV-positive youth, aged 14–25 years. Measurements included self-reported tobacco use, fasting lipids, glucose, fat distribution, and bone mineral density (BMD; dual-energy X-ray absorptiometry scans). Overall, 144 (38.7%) self-reported smoking tobacco and 69 (47.9%) of these reported smoking greater than five cigarettes per day. Smokers versus nonsmokers had lower mean total cholesterol (146.0 versus 156.1 mg/dL; P<0.01) and lower mean total body fat percent (24.1% versus 27.2%, P=0.03). There was no difference between smokers and nonsmokers in fasting glucose or BMD. There appear to be only minimal effects from tobacco smoking on markers of cardiac risk and bone health in this population of HIV-positive youth. While these smokers may not have had sufficient exposure to tobacco to detect changes in the outcome measures, given the long-term risks associated with smoking and HIV, it is critical that we encourage HIV-positive youth smokers to quit before the deleterious effects become apparent. |
| format | Article |
| id | doaj-art-30928838d2244bb0b4dbe396b6e98df2 |
| institution | Kabale University |
| issn | 2090-1240 2090-1259 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | AIDS Research and Treatment |
| spelling | doaj-art-30928838d2244bb0b4dbe396b6e98df22025-02-03T06:12:12ZengWileyAIDS Research and Treatment2090-12402090-12592014-01-01201410.1155/2014/740545740545Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIVMark L. Rubinstein0D. Robert Harris1Bret J. Rudy2Bill G. Kapogiannis3Grace M. Aldrovandi4Kathleen Mulligan5University of California, San Francisco, San Francisco, CA 94117, USAWestat, Rockville, MD 20850, USANew York University School of Medicine, New York, NY 10016, USAMaternal and Pediatric Infectious Diseases Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USAChildren’s Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USAUniversity of California, San Francisco, San Francisco, CA 94117, USAWe conducted cross-sectional, multicenter studies in HIV-positive young women and men to assess metabolic and morphologic complications from tobacco smoking in 372 behaviorally infected HIV-positive youth, aged 14–25 years. Measurements included self-reported tobacco use, fasting lipids, glucose, fat distribution, and bone mineral density (BMD; dual-energy X-ray absorptiometry scans). Overall, 144 (38.7%) self-reported smoking tobacco and 69 (47.9%) of these reported smoking greater than five cigarettes per day. Smokers versus nonsmokers had lower mean total cholesterol (146.0 versus 156.1 mg/dL; P<0.01) and lower mean total body fat percent (24.1% versus 27.2%, P=0.03). There was no difference between smokers and nonsmokers in fasting glucose or BMD. There appear to be only minimal effects from tobacco smoking on markers of cardiac risk and bone health in this population of HIV-positive youth. While these smokers may not have had sufficient exposure to tobacco to detect changes in the outcome measures, given the long-term risks associated with smoking and HIV, it is critical that we encourage HIV-positive youth smokers to quit before the deleterious effects become apparent.http://dx.doi.org/10.1155/2014/740545 |
| spellingShingle | Mark L. Rubinstein D. Robert Harris Bret J. Rudy Bill G. Kapogiannis Grace M. Aldrovandi Kathleen Mulligan Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV AIDS Research and Treatment |
| title | Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV |
| title_full | Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV |
| title_fullStr | Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV |
| title_full_unstemmed | Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV |
| title_short | Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV |
| title_sort | exploration of the effect of tobacco smoking on metabolic measures in young people living with hiv |
| url | http://dx.doi.org/10.1155/2014/740545 |
| work_keys_str_mv | AT marklrubinstein explorationoftheeffectoftobaccosmokingonmetabolicmeasuresinyoungpeoplelivingwithhiv AT drobertharris explorationoftheeffectoftobaccosmokingonmetabolicmeasuresinyoungpeoplelivingwithhiv AT bretjrudy explorationoftheeffectoftobaccosmokingonmetabolicmeasuresinyoungpeoplelivingwithhiv AT billgkapogiannis explorationoftheeffectoftobaccosmokingonmetabolicmeasuresinyoungpeoplelivingwithhiv AT gracemaldrovandi explorationoftheeffectoftobaccosmokingonmetabolicmeasuresinyoungpeoplelivingwithhiv AT kathleenmulligan explorationoftheeffectoftobaccosmokingonmetabolicmeasuresinyoungpeoplelivingwithhiv |