Comparison of genetic mutations in bladder cancers that arose following radiotherapy for prostate cancer with those in primary bladder cancers

Comparison of genetic mutations in bladder cancers that arose following radiotherapy for prostate cancer with those in primary bladder cancers

Abstract Radiotherapy (RT) for prostate cancer increases the risk of bladder cancer. The genomic landscape of bladder cancer following RT for prostate cancer and its differentiation from bladder cancers that develop without a history of pelvic RT remains unclear. We examined gene mutations in bladde...

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Main Authors: Shogo Adomi, Kazuko Sakai, Yurie Kura, Marco A De Velasco, Saizo Fujimoto, Shingo Toyoda, Mamoru Hashimoto, Mitsuhisa Nishimoto, Eri Banno, Yoshitaka Saito, Koichi Sugimoto, Yujiro Hayashi, Takafumi Minami, Kazuhiro Yoshimura, Hirotsugu Uemura, Kazuto Nishio, Kazutoshi Fujita
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-05149-z
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