Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis
<b>Objectives</b>: The aim of this systematic review and meta-analysis was to compare whether osteopathic manipulative treatment (OMT) for somatic dysfunctions was more effective than sham or placebo interventions in improving pain intensity, disability, and quality of life for patients...
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MDPI AG
2024-11-01
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| author | Luis Ceballos-Laita Sandra Jiménez-del-Barrio Andoni Carrasco-Uribarren Ricardo Medrano-de-la-Fuente Román Robles-Pérez Edzard Ernst |
| author_facet | Luis Ceballos-Laita Sandra Jiménez-del-Barrio Andoni Carrasco-Uribarren Ricardo Medrano-de-la-Fuente Román Robles-Pérez Edzard Ernst |
| author_sort | Luis Ceballos-Laita |
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| description | <b>Objectives</b>: The aim of this systematic review and meta-analysis was to compare whether osteopathic manipulative treatment (OMT) for somatic dysfunctions was more effective than sham or placebo interventions in improving pain intensity, disability, and quality of life for patients with neck pain (NP) or low-back pain (LBP). <b>Methods</b>: A systematic review and meta-analysis was carried out. Searches were conducted in PubMed, Physiotherapy Evidence Database, Cochrane Library, and Web of Science from inception to September 2024. Studies applying a pragmatic intervention based on the diagnosis of somatic dysfunctions in patients with NP or LBP were included. The methodological quality was assessed with the PEDro scale. The quantitative synthesis was performed using random-effect meta-analysis calculating the standardized mean difference (SMD) with RevMan 5.4. The certainty of evidence was evaluated using GRADEPro. <b>Results</b>: Nine studies were included in the qualitative synthesis, and most of them showed no superior effect of OMTs compared to sham or placebo in any clinical outcome. The quantitative synthesis reported no statistically significant differences for pain intensity (SMD = −0.15; −0.38, 0.08; seven studies; 1173 patients) or disability (SMD = −0.09; −0.25, 0.08; six studies; 1153 patients). The certainty of evidence was downgraded to moderate, low, or very low. <b>Conclusions</b>: The findings of this study reveal that OMT is not superior to sham or placebo for improving pain, disability, and quality of life in patients with NP or LBP. |
| format | Article |
| id | doaj-art-3077c775ff6249e18ef3439453065cc0 |
| institution | OA Journals |
| issn | 2079-9721 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diseases |
| spelling | doaj-art-3077c775ff6249e18ef3439453065cc02025-08-20T01:53:45ZengMDPI AGDiseases2079-97212024-11-01121128710.3390/diseases12110287Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-AnalysisLuis Ceballos-Laita0Sandra Jiménez-del-Barrio1Andoni Carrasco-Uribarren2Ricardo Medrano-de-la-Fuente3Román Robles-Pérez4Edzard Ernst5Grupo de Investigación Clínica en Ciencias de la Salud, Departamento de Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia, Universidad de Valladolid, Campus Duques de Soria, 42004 Soria, SpainGrupo de Investigación Clínica en Ciencias de la Salud, Departamento de Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia, Universidad de Valladolid, Campus Duques de Soria, 42004 Soria, SpainDepartamento de Fisioterapia, Universidad Internacional de Cataluña, 08195 Sant Cugat del Valles, SpainGrupo de Investigación Clínica en Ciencias de la Salud, Departamento de Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia, Universidad de Valladolid, Campus Duques de Soria, 42004 Soria, SpainGrupo de Investigación Clínica en Ciencias de la Salud, Departamento de Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia, Universidad de Valladolid, Campus Duques de Soria, 42004 Soria, SpainEmeritus Professor, University of Exeter, Exeter EX4 4PY, UK<b>Objectives</b>: The aim of this systematic review and meta-analysis was to compare whether osteopathic manipulative treatment (OMT) for somatic dysfunctions was more effective than sham or placebo interventions in improving pain intensity, disability, and quality of life for patients with neck pain (NP) or low-back pain (LBP). <b>Methods</b>: A systematic review and meta-analysis was carried out. Searches were conducted in PubMed, Physiotherapy Evidence Database, Cochrane Library, and Web of Science from inception to September 2024. Studies applying a pragmatic intervention based on the diagnosis of somatic dysfunctions in patients with NP or LBP were included. The methodological quality was assessed with the PEDro scale. The quantitative synthesis was performed using random-effect meta-analysis calculating the standardized mean difference (SMD) with RevMan 5.4. The certainty of evidence was evaluated using GRADEPro. <b>Results</b>: Nine studies were included in the qualitative synthesis, and most of them showed no superior effect of OMTs compared to sham or placebo in any clinical outcome. The quantitative synthesis reported no statistically significant differences for pain intensity (SMD = −0.15; −0.38, 0.08; seven studies; 1173 patients) or disability (SMD = −0.09; −0.25, 0.08; six studies; 1153 patients). The certainty of evidence was downgraded to moderate, low, or very low. <b>Conclusions</b>: The findings of this study reveal that OMT is not superior to sham or placebo for improving pain, disability, and quality of life in patients with NP or LBP.https://www.mdpi.com/2079-9721/12/11/287osteopathyosteopathic manipulative treatmentneck painlow-back pain |
| spellingShingle | Luis Ceballos-Laita Sandra Jiménez-del-Barrio Andoni Carrasco-Uribarren Ricardo Medrano-de-la-Fuente Román Robles-Pérez Edzard Ernst Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis Diseases osteopathy osteopathic manipulative treatment neck pain low-back pain |
| title | Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis |
| title_full | Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis |
| title_fullStr | Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis |
| title_full_unstemmed | Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis |
| title_short | Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis |
| title_sort | is osteopathic manipulative treatment clinically superior to sham or placebo for patients with neck or low back pain a systematic review with meta analysis |
| topic | osteopathy osteopathic manipulative treatment neck pain low-back pain |
| url | https://www.mdpi.com/2079-9721/12/11/287 |
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