Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts
The recent recognition of neurocysticercosis as a major cause of epilepsy in Uganda and changes in pig demography have lead to a need to better understand the basic epidemiology of Taenia solium infections in pigs and humans. Human exposure is a function of the size of the animal reservoir of this...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Journal of Parasitology Research |
| Online Access: | http://dx.doi.org/10.1155/2009/375493 |
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| author | C. Waiswa E. M. Fèvre Z. Nsadha C. S. Sikasunge A. L. Willingham |
| author_facet | C. Waiswa E. M. Fèvre Z. Nsadha C. S. Sikasunge A. L. Willingham |
| author_sort | C. Waiswa |
| collection | DOAJ |
| description | The recent recognition of neurocysticercosis as a major cause of epilepsy in Uganda and changes in pig demography have lead to a need to better understand the basic epidemiology of Taenia solium infections in pigs and humans. Human exposure is a function of the size of the animal reservoir of this zoonosis. This is the first field survey for porcine cysticercosis to investigate the prevalence of antigen-positive pigs across an entire rural district of south-east Uganda. In our field surveys, 8.6% of 480 pigs screened were seropositive for the parasite by B158/B60 Ag-ELISA. In addition, of the 528 homesteads surveyed 138 (26%) did not have pit latrines indicating a high probability of pigs having access to human faeces and thus T. solium eggs. This study thus indicates the need for better data on this neglected zoonotic disease in Uganda, with a particular emphasis on the risk factors for infection in both pigs and humans. In this regard, further surveys of pigs, seroprevalence surveys in humans and an understanding of cysticercosis-related epilepsy are required, together with risk-factor studies for human and porcine infections. |
| format | Article |
| id | doaj-art-3071b105681a4cd09c4400ba4e70ffd2 |
| institution | Kabale University |
| issn | 2090-0023 2090-0031 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Parasitology Research |
| spelling | doaj-art-3071b105681a4cd09c4400ba4e70ffd22025-02-03T05:45:05ZengWileyJournal of Parasitology Research2090-00232090-00312009-01-01200910.1155/2009/375493375493Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro DistrictsC. Waiswa0E. M. Fèvre1Z. Nsadha2C. S. Sikasunge3A. L. Willingham4Faculty of Veterinary Medicine, Makerere University, P.O. Box 7062, Kampala, UgandaCentre for Infectious Diseases, School of Biological Sciences, University of Edinburgh, Ashworth Laboratories, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UKFaculty of Veterinary Medicine, Makerere University, P.O. Box 7062, Kampala, UgandaSchool of Veterinary Medicine, University of Zambia, P.O. Box 32379, Lusaka, ZambiaWHO/FAO Collaborating Centre for Research and Training for Emerging and Other Parasitic Zoonoses, Parasitology, Health and Development Section, Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Dyrelægevej 100, 1870 Frederiksberg C, DenmarkThe recent recognition of neurocysticercosis as a major cause of epilepsy in Uganda and changes in pig demography have lead to a need to better understand the basic epidemiology of Taenia solium infections in pigs and humans. Human exposure is a function of the size of the animal reservoir of this zoonosis. This is the first field survey for porcine cysticercosis to investigate the prevalence of antigen-positive pigs across an entire rural district of south-east Uganda. In our field surveys, 8.6% of 480 pigs screened were seropositive for the parasite by B158/B60 Ag-ELISA. In addition, of the 528 homesteads surveyed 138 (26%) did not have pit latrines indicating a high probability of pigs having access to human faeces and thus T. solium eggs. This study thus indicates the need for better data on this neglected zoonotic disease in Uganda, with a particular emphasis on the risk factors for infection in both pigs and humans. In this regard, further surveys of pigs, seroprevalence surveys in humans and an understanding of cysticercosis-related epilepsy are required, together with risk-factor studies for human and porcine infections.http://dx.doi.org/10.1155/2009/375493 |
| spellingShingle | C. Waiswa E. M. Fèvre Z. Nsadha C. S. Sikasunge A. L. Willingham Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts Journal of Parasitology Research |
| title | Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts |
| title_full | Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts |
| title_fullStr | Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts |
| title_full_unstemmed | Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts |
| title_short | Porcine Cysticercosis in Southeast Uganda: Seroprevalence in Kamuli and Kaliro Districts |
| title_sort | porcine cysticercosis in southeast uganda seroprevalence in kamuli and kaliro districts |
| url | http://dx.doi.org/10.1155/2009/375493 |
| work_keys_str_mv | AT cwaiswa porcinecysticercosisinsoutheastugandaseroprevalenceinkamuliandkalirodistricts AT emfevre porcinecysticercosisinsoutheastugandaseroprevalenceinkamuliandkalirodistricts AT znsadha porcinecysticercosisinsoutheastugandaseroprevalenceinkamuliandkalirodistricts AT cssikasunge porcinecysticercosisinsoutheastugandaseroprevalenceinkamuliandkalirodistricts AT alwillingham porcinecysticercosisinsoutheastugandaseroprevalenceinkamuliandkalirodistricts |