Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature
Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma originating from fibroblasts in the dermal connective tissue, comprising approximately 1% of all soft tissue sarcomas. While most cases involve the trunk and extremities, only 10%–15% occur in the cephalic region, representing less...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/crom/9991548 |
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| author | Ulrich Igor Mbessoh Kengne Jaafar Ibn Abou Talib Thiam Amacoumba Fall Salif Balde Mamadou Ndiaye Joel Gabin Konlack Mekontso Gorgui Sarr Etienne Tossou Zoure Mamadou Sow Sidy Ka |
| author_facet | Ulrich Igor Mbessoh Kengne Jaafar Ibn Abou Talib Thiam Amacoumba Fall Salif Balde Mamadou Ndiaye Joel Gabin Konlack Mekontso Gorgui Sarr Etienne Tossou Zoure Mamadou Sow Sidy Ka |
| author_sort | Ulrich Igor Mbessoh Kengne |
| collection | DOAJ |
| description | Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma originating from fibroblasts in the dermal connective tissue, comprising approximately 1% of all soft tissue sarcomas. While most cases involve the trunk and extremities, only 10%–15% occur in the cephalic region, representing less than 1% of all head and neck neoplasms. DFSP is notable for its high propensity for local recurrence following surgical excision and its low metastatic potential. We report a case of recurrent DFSP of the forehead extending to the anterior wall of the left frontal sinus, without brain involvement, in a 33-year-old male with a history of three prior wide local excisions. A multidisciplinary cancer team recommended systemic imatinib therapy. This case highlights the challenges of managing DFSP in an uncommon location, underscoring the importance of a multidisciplinary approach in addressing recurrent and complex presentations. |
| format | Article |
| id | doaj-art-306ebbb4f87b486cbe5fb226b8d5eff3 |
| institution | DOAJ |
| issn | 2090-6714 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-306ebbb4f87b486cbe5fb226b8d5eff32025-08-20T03:10:24ZengWileyCase Reports in Oncological Medicine2090-67142025-01-01202510.1155/crom/9991548Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of LiteratureUlrich Igor Mbessoh Kengne0Jaafar Ibn Abou Talib Thiam1Amacoumba Fall2Salif Balde3Mamadou Ndiaye4Joel Gabin Konlack Mekontso5Gorgui Sarr6Etienne Tossou Zoure7Mamadou Sow8Sidy Ka9Department of Surgical OncologyDepartment of Surgical OncologyDepartment of Surgical OncologyDepartment of Medical OncologyDepartment of Surgical OncologyDepartment of Internal MedicineDepartment of Surgical OncologyDepartment of Surgical OncologyDepartment of Surgical OncologyDepartment of Surgical OncologyDermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma originating from fibroblasts in the dermal connective tissue, comprising approximately 1% of all soft tissue sarcomas. While most cases involve the trunk and extremities, only 10%–15% occur in the cephalic region, representing less than 1% of all head and neck neoplasms. DFSP is notable for its high propensity for local recurrence following surgical excision and its low metastatic potential. We report a case of recurrent DFSP of the forehead extending to the anterior wall of the left frontal sinus, without brain involvement, in a 33-year-old male with a history of three prior wide local excisions. A multidisciplinary cancer team recommended systemic imatinib therapy. This case highlights the challenges of managing DFSP in an uncommon location, underscoring the importance of a multidisciplinary approach in addressing recurrent and complex presentations.http://dx.doi.org/10.1155/crom/9991548 |
| spellingShingle | Ulrich Igor Mbessoh Kengne Jaafar Ibn Abou Talib Thiam Amacoumba Fall Salif Balde Mamadou Ndiaye Joel Gabin Konlack Mekontso Gorgui Sarr Etienne Tossou Zoure Mamadou Sow Sidy Ka Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature Case Reports in Oncological Medicine |
| title | Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature |
| title_full | Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature |
| title_fullStr | Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature |
| title_full_unstemmed | Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature |
| title_short | Dermatofibrosarcoma Protuberans of the Forehead: Case Report of a Rare Entity and Review of Literature |
| title_sort | dermatofibrosarcoma protuberans of the forehead case report of a rare entity and review of literature |
| url | http://dx.doi.org/10.1155/crom/9991548 |
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