Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease
Histiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diff...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2020/4674103 |
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| author | Amrit P. Singh Glenn P. Murray Soumya Pandey |
| author_facet | Amrit P. Singh Glenn P. Murray Soumya Pandey |
| author_sort | Amrit P. Singh |
| collection | DOAJ |
| description | Histiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diffuse large B-cell lymphoma (DLBCL), status postchemoradiation therapy, who developed HRPT at the site of original involvement, mimicking relapse of disease on positron emission tomography/computed tomography (PET/CT) imaging. This is one of the few reported cases of posttreatment HRPT. This entity is important to point out the limitations of PET/CT imaging in patients with lymphomas and metastatic disease and stresses the importance of an excisional biopsy for determining relapse and the need for further treatment. |
| format | Article |
| id | doaj-art-305877f7607e4038b09a5b955f192f9b |
| institution | DOAJ |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-305877f7607e4038b09a5b955f192f9b2025-08-20T03:20:23ZengWileyCase Reports in Pathology2090-67812090-679X2020-01-01202010.1155/2020/46741034674103Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual DiseaseAmrit P. Singh0Glenn P. Murray1Soumya Pandey2Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USADepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USADepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USAHistiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diffuse large B-cell lymphoma (DLBCL), status postchemoradiation therapy, who developed HRPT at the site of original involvement, mimicking relapse of disease on positron emission tomography/computed tomography (PET/CT) imaging. This is one of the few reported cases of posttreatment HRPT. This entity is important to point out the limitations of PET/CT imaging in patients with lymphomas and metastatic disease and stresses the importance of an excisional biopsy for determining relapse and the need for further treatment.http://dx.doi.org/10.1155/2020/4674103 |
| spellingShingle | Amrit P. Singh Glenn P. Murray Soumya Pandey Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease Case Reports in Pathology |
| title | Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease |
| title_full | Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease |
| title_fullStr | Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease |
| title_full_unstemmed | Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease |
| title_short | Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease |
| title_sort | benign histiocyte rich pseudotumor developing postchemotherapy and mimicking residual disease |
| url | http://dx.doi.org/10.1155/2020/4674103 |
| work_keys_str_mv | AT amritpsingh benignhistiocyterichpseudotumordevelopingpostchemotherapyandmimickingresidualdisease AT glennpmurray benignhistiocyterichpseudotumordevelopingpostchemotherapyandmimickingresidualdisease AT soumyapandey benignhistiocyterichpseudotumordevelopingpostchemotherapyandmimickingresidualdisease |