Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer

Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer

Abstract Breast cancer (BC) is a heterogeneous disease, traditionally classified by hormone receptor and HER2 (human epidermal growth factor receptor 2) status. HER2-low, characterized by low HER2 expression without gene amplification, recently gained attention. While new therapies are promising, it...

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Main Authors: Maria Elena Lacruz, Saskia Thies, Andrea Schmidt-Pokrzywniak, Ian Wittenberg, Tobias Engler, Fabian Reinwald, Monika Klinkhammer-Schalke, Sylke Ruth Zeissig, Bianca Franke, Kerstin Weitmann, Atanas Ignatov
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Breast cancer
HER2 (human epidermal growth factor receptor 2) status
Metastasis
Metastasis-free survival (MFS)
Recurrence-free survival (RFS)
Overall survival (OS)
Online Access:https://doi.org/10.1038/s41598-025-88394-6
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https://doi.org/10.1038/s41598-025-88394-6

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