Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County
Objective: Vaccination plays a crucial role in preventing severe lung disease and reducing hospitalization rates among patients with coronavirus disease-2019 (COVID-19). In this study, researchers compared lung computed tomography (CT) scans of vaccinated and unvaccinated individuals with COVID-19,...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2025-01-01
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| Series: | Gazi Medical Journal |
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| Online Access: | https://gazimedj.com/articles/comparison-of-computerized-tomography-ct-scan-clinical-and-para-clinical-findings-in-hospitalized-vaccinated-and-unvaccinated-covid-19-patients-a-pilot-study-from-babol-county/doi/gmj.2024.3946 |
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| author | Hesamoddin Arabnozari Farzin Sadeghi Mohammadreza Tabatabaie Ghazaleh Hosseininozari Mana Baziboron Masoumeh Bayani |
| author_facet | Hesamoddin Arabnozari Farzin Sadeghi Mohammadreza Tabatabaie Ghazaleh Hosseininozari Mana Baziboron Masoumeh Bayani |
| author_sort | Hesamoddin Arabnozari |
| collection | DOAJ |
| description | Objective: Vaccination plays a crucial role in preventing severe lung disease and reducing hospitalization rates among patients with coronavirus disease-2019 (COVID-19). In this study, researchers compared lung computed tomography (CT) scans of vaccinated and unvaccinated individuals with COVID-19, along with clinical and para-clinical findings.
Methods: This study was conducted at Ayatollah Rouhani Hospital in Babol, Iran, between July and November 2021. The researchers selected 106 confirmed COVID-19 patients and divided them into two groups: 53 fully vaccinated individuals who received the Sinopharm vaccine and 53 unvaccinated individuals. Demographics, laboratory, and imaging data were collected.
Results: The mean age of hospitalized patients with COVID-19 was 59.8±16.1 years. The most common CT finding in both groups was bilateral ground glass opacities, observed in 95 patients (89.6%). Significant associations were found between the vaccinated and unvaccinated groups regarding hospital stay duration, oxygen saturation, intensive care unit admission, lactate dehydrogenase levels, and erythrocyte sedimentation rate index.
Conclusion: This study revealed no difference in the pattern of pulmonary involvement between vaccinated and unvaccinated individuals with COVID-19, except for the peribronchovascular pattern, which was more commonly observed in unvaccinated patients. Other common patterns of pulmonary involvement were also more prevalent among unvaccinated individuals. These findings emphasize the effectiveness of COVID-19 vaccination, as the vaccinated group had a lower rate of pulmonary involvement. This highlights the need for widespread vaccination to effectively combat COVID-19. |
| format | Article |
| id | doaj-art-305067529e1e4483985c983fc32b29ea |
| institution | Kabale University |
| issn | 2147-2092 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Gazi Medical Journal |
| spelling | doaj-art-305067529e1e4483985c983fc32b29ea2025-01-13T11:20:51ZengGalenos Publishing HouseGazi Medical Journal2147-20922025-01-0136151010.12996/gmj.2024.3946Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol CountyHesamoddin Arabnozari0https://orcid.org/0009-0002-2041-0253Farzin Sadeghi1https://orcid.org/0000-0001-8599-3643Mohammadreza Tabatabaie2https://orcid.org/0000-0002-7634-9877Ghazaleh Hosseininozari3https://orcid.org/0009-0008-0616-9516Mana Baziboron4https://orcid.org/0000-0001-6251-9682Masoumeh Bayani5https://orcid.org/0000-0003-3044-1168Student Research Committee, Babol University of Medical Sciences Faculty of Medicine, Babol, IranCellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranClinic of Radiology, Babol University of Medical Sciences, Rouhani Hospital, Babol, IranDepartment of Cell and Molecular Biology, Islamic Azad University, Babol, IranInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranDepartment of Infectious Disease, Babol University of Medical Sciences Faculty of Medicine, Babol, IranObjective: Vaccination plays a crucial role in preventing severe lung disease and reducing hospitalization rates among patients with coronavirus disease-2019 (COVID-19). In this study, researchers compared lung computed tomography (CT) scans of vaccinated and unvaccinated individuals with COVID-19, along with clinical and para-clinical findings. Methods: This study was conducted at Ayatollah Rouhani Hospital in Babol, Iran, between July and November 2021. The researchers selected 106 confirmed COVID-19 patients and divided them into two groups: 53 fully vaccinated individuals who received the Sinopharm vaccine and 53 unvaccinated individuals. Demographics, laboratory, and imaging data were collected. Results: The mean age of hospitalized patients with COVID-19 was 59.8±16.1 years. The most common CT finding in both groups was bilateral ground glass opacities, observed in 95 patients (89.6%). Significant associations were found between the vaccinated and unvaccinated groups regarding hospital stay duration, oxygen saturation, intensive care unit admission, lactate dehydrogenase levels, and erythrocyte sedimentation rate index. Conclusion: This study revealed no difference in the pattern of pulmonary involvement between vaccinated and unvaccinated individuals with COVID-19, except for the peribronchovascular pattern, which was more commonly observed in unvaccinated patients. Other common patterns of pulmonary involvement were also more prevalent among unvaccinated individuals. These findings emphasize the effectiveness of COVID-19 vaccination, as the vaccinated group had a lower rate of pulmonary involvement. This highlights the need for widespread vaccination to effectively combat COVID-19.https://gazimedj.com/articles/comparison-of-computerized-tomography-ct-scan-clinical-and-para-clinical-findings-in-hospitalized-vaccinated-and-unvaccinated-covid-19-patients-a-pilot-study-from-babol-county/doi/gmj.2024.3946covid 19vaccinesx-ray computed tomography |
| spellingShingle | Hesamoddin Arabnozari Farzin Sadeghi Mohammadreza Tabatabaie Ghazaleh Hosseininozari Mana Baziboron Masoumeh Bayani Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County Gazi Medical Journal covid 19 vaccines x-ray computed tomography |
| title | Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County |
| title_full | Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County |
| title_fullStr | Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County |
| title_full_unstemmed | Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County |
| title_short | Comparison of Computerized Tomography (CT) Scan, Clinical and Para-clinical Findings in Hospitalized Vaccinated and Unvaccinated COVID-19 Patients: A Pilot Study from Babol County |
| title_sort | comparison of computerized tomography ct scan clinical and para clinical findings in hospitalized vaccinated and unvaccinated covid 19 patients a pilot study from babol county |
| topic | covid 19 vaccines x-ray computed tomography |
| url | https://gazimedj.com/articles/comparison-of-computerized-tomography-ct-scan-clinical-and-para-clinical-findings-in-hospitalized-vaccinated-and-unvaccinated-covid-19-patients-a-pilot-study-from-babol-county/doi/gmj.2024.3946 |
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