Contrast-enhanced mammography in breast cancer screening: Our experiences
Background/Aim. Breast cancer is a leading global health concern. Contrast-enhanced mammography (CEM) presents a promising advancement in early breast cancer detection, excelling in sensitivity, specificity, and cost-effectiveness. The aim of the study was to assess the overall diagnostic efficacy o...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2025-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | https://doiserbia.nb.rs/img/doi/0042-8450/2025/0042-84502500005N.pdf |
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| author | Nićiforović Dijana Basta-Nikolić Marijana Drvendžija Zorka Nikolić Olivera Mijatović Aleksandra Lukač Sonja Stojanović Sanja |
| author_facet | Nićiforović Dijana Basta-Nikolić Marijana Drvendžija Zorka Nikolić Olivera Mijatović Aleksandra Lukač Sonja Stojanović Sanja |
| author_sort | Nićiforović Dijana |
| collection | DOAJ |
| description | Background/Aim. Breast cancer is a leading global health concern. Contrast-enhanced mammography (CEM) presents a promising advancement in early breast cancer detection, excelling in sensitivity, specificity, and cost-effectiveness. The aim of the study was to assess the overall diagnostic efficacy of CEM in breast cancer screening, particularly in distinguishing benign from malignant lesions in dense breasts. Methods. A two-year retrospective study was conducted at the Center for Radiology, including a total of 279 women undergoing CEM following standard mammography. Results. CEM demonstrated high sensitivity (92.4%), specificity (75.1%), and a noteworthy negative predictive value of 97.0%, significantly reducing unnecessary biopsies. Conclusion. CEM is a valuable screening tool, offering enhanced diagnostic capabilities and the potential to reduce the number of unnecessary biopsies. It is particularly beneficial for patients with dense breasts or inconclusive traditional mammography results. |
| format | Article |
| id | doaj-art-304b4b7d3f0942e79ef84a9fe39e706d |
| institution | DOAJ |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-304b4b7d3f0942e79ef84a9fe39e706d2025-08-20T03:20:23ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202025-01-01822869310.2298/VSP240606005N0042-84502500005NContrast-enhanced mammography in breast cancer screening: Our experiencesNićiforović Dijana0Basta-Nikolić Marijana1https://orcid.org/0000-0003-2769-886XDrvendžija Zorka2Nikolić Olivera3Mijatović Aleksandra4Lukač Sonja5https://orcid.org/0009-0002-7984-7062Stojanović Sanja6https://orcid.org/0000-0002-3011-5218University Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia University Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia University Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia University Clinical Center of Vojvodina, Center for Radiology, Novi Sad, SerbiaUniversity Clinical Center of Vojvodina, Center for Radiology, Novi Sad, SerbiaUniversity Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia Background/Aim. Breast cancer is a leading global health concern. Contrast-enhanced mammography (CEM) presents a promising advancement in early breast cancer detection, excelling in sensitivity, specificity, and cost-effectiveness. The aim of the study was to assess the overall diagnostic efficacy of CEM in breast cancer screening, particularly in distinguishing benign from malignant lesions in dense breasts. Methods. A two-year retrospective study was conducted at the Center for Radiology, including a total of 279 women undergoing CEM following standard mammography. Results. CEM demonstrated high sensitivity (92.4%), specificity (75.1%), and a noteworthy negative predictive value of 97.0%, significantly reducing unnecessary biopsies. Conclusion. CEM is a valuable screening tool, offering enhanced diagnostic capabilities and the potential to reduce the number of unnecessary biopsies. It is particularly beneficial for patients with dense breasts or inconclusive traditional mammography results.https://doiserbia.nb.rs/img/doi/0042-8450/2025/0042-84502500005N.pdfbreast cancerdiagnosisdifferential diagnosismammographymass screeningsensitivity and specificityultrasonographymammary |
| spellingShingle | Nićiforović Dijana Basta-Nikolić Marijana Drvendžija Zorka Nikolić Olivera Mijatović Aleksandra Lukač Sonja Stojanović Sanja Contrast-enhanced mammography in breast cancer screening: Our experiences Vojnosanitetski Pregled breast cancer diagnosis differential diagnosis mammography mass screening sensitivity and specificity ultrasonography mammary |
| title | Contrast-enhanced mammography in breast cancer screening: Our experiences |
| title_full | Contrast-enhanced mammography in breast cancer screening: Our experiences |
| title_fullStr | Contrast-enhanced mammography in breast cancer screening: Our experiences |
| title_full_unstemmed | Contrast-enhanced mammography in breast cancer screening: Our experiences |
| title_short | Contrast-enhanced mammography in breast cancer screening: Our experiences |
| title_sort | contrast enhanced mammography in breast cancer screening our experiences |
| topic | breast cancer diagnosis differential diagnosis mammography mass screening sensitivity and specificity ultrasonography mammary |
| url | https://doiserbia.nb.rs/img/doi/0042-8450/2025/0042-84502500005N.pdf |
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