Contrast-enhanced mammography in breast cancer screening: Our experiences

Background/Aim. Breast cancer is a leading global health concern. Contrast-enhanced mammography (CEM) presents a promising advancement in early breast cancer detection, excelling in sensitivity, specificity, and cost-effectiveness. The aim of the study was to assess the overall diagnostic efficacy o...

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Bibliographic Details
Main Authors: Nićiforović Dijana, Basta-Nikolić Marijana, Drvendžija Zorka, Nikolić Olivera, Mijatović Aleksandra, Lukač Sonja, Stojanović Sanja
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2025-01-01
Series:Vojnosanitetski Pregled
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Online Access:https://doiserbia.nb.rs/img/doi/0042-8450/2025/0042-84502500005N.pdf
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Summary:Background/Aim. Breast cancer is a leading global health concern. Contrast-enhanced mammography (CEM) presents a promising advancement in early breast cancer detection, excelling in sensitivity, specificity, and cost-effectiveness. The aim of the study was to assess the overall diagnostic efficacy of CEM in breast cancer screening, particularly in distinguishing benign from malignant lesions in dense breasts. Methods. A two-year retrospective study was conducted at the Center for Radiology, including a total of 279 women undergoing CEM following standard mammography. Results. CEM demonstrated high sensitivity (92.4%), specificity (75.1%), and a noteworthy negative predictive value of 97.0%, significantly reducing unnecessary biopsies. Conclusion. CEM is a valuable screening tool, offering enhanced diagnostic capabilities and the potential to reduce the number of unnecessary biopsies. It is particularly beneficial for patients with dense breasts or inconclusive traditional mammography results.
ISSN:0042-8450
2406-0720