Druggability and molecular docking of essential secondary metabolites from Azadirachta indica leaf against angiotensin converting enzyme-2: Covid-19 in focus

Druggability and molecular docking of essential secondary metabolites from Azadirachta indica leaf against angiotensin converting enzyme-2: Covid-19 in focus

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious and virulent coronavirus that arose in late 2019 and poses great risk to public health and safety. The SARS-CoV-2 utilizes peptidase, angiotensin-converting enzyme 2 (ACE2) for entrance and invasion into host cells....

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Bibliographic Details
Main Authors: Paul Chijioke Ozioko, Ukamaka Owohetete, Daniel Danladi Gaiya
Format: Article
Language:English
Published: University of Nigeria 2025-02-01
Series:African Journal of Pharmaceutical Research and Development (AJOPRED)
Subjects:
Azadirachta indica
Druggability
SARS-CoV-2
Angiotensin converting enzyme-2
Molecular docking
ACE-2
Online Access:https://www.ajol.info/index.php/ajopred/article/view/288097
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