The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials
A novel biomedical material composed of spherical hydroxyapatite (s-HA) and polyamide 66 (PA) biocomposite (s-HA/PA) was prepared, and its composition, mechanical properties, and cytocompatibility were characterized and evaluated. The results showed that HA distributed uniformly in the s-HA/PA matri...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2014/579252 |
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| author | Xuesong Zhang Ming Lu Yan Wang Xiaojing Su Xuelian Zhang |
| author_facet | Xuesong Zhang Ming Lu Yan Wang Xiaojing Su Xuelian Zhang |
| author_sort | Xuesong Zhang |
| collection | DOAJ |
| description | A novel biomedical material composed of spherical hydroxyapatite (s-HA) and polyamide 66 (PA) biocomposite (s-HA/PA) was prepared, and its composition, mechanical properties, and cytocompatibility were characterized and evaluated. The results showed that HA distributed uniformly in the s-HA/PA matrix. Strong molecule interactions and chemical bonds were presented between the s-HA and PA in the composites confirmed by IR and XRD. The composite had excellent compressive strength in the range between 95 and 132 MPa, close to that of natural bone. In vitro experiments showed the s-HA/PA composite could improve cell growth, proliferation, and differentiation. Therefore, the developed s-HA/PA composites in this study might be used for tissue engineering and bone repair. |
| format | Article |
| id | doaj-art-3041a4e902d944388a682b0c3ffe4c0d |
| institution | OA Journals |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-3041a4e902d944388a682b0c3ffe4c0d2025-08-20T02:07:53ZengWileyInternational Journal of Polymer Science1687-94221687-94302014-01-01201410.1155/2014/579252579252The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair MaterialsXuesong Zhang0Ming Lu1Yan Wang2Xiaojing Su3Xuelian Zhang4Department of Orthopaedics, Chinese People’s Liberation Army General Hospital, Beijing 100853, ChinaDepartment of Orthopaedics, Chinese People’s Liberation Army General Hospital, Beijing 100853, ChinaDepartment of Orthopaedics, Chinese People’s Liberation Army General Hospital, Beijing 100853, ChinaDepartment of Orthopaedics, Chinese People’s Liberation Army General Hospital, Beijing 100853, ChinaDepartment of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, ChinaA novel biomedical material composed of spherical hydroxyapatite (s-HA) and polyamide 66 (PA) biocomposite (s-HA/PA) was prepared, and its composition, mechanical properties, and cytocompatibility were characterized and evaluated. The results showed that HA distributed uniformly in the s-HA/PA matrix. Strong molecule interactions and chemical bonds were presented between the s-HA and PA in the composites confirmed by IR and XRD. The composite had excellent compressive strength in the range between 95 and 132 MPa, close to that of natural bone. In vitro experiments showed the s-HA/PA composite could improve cell growth, proliferation, and differentiation. Therefore, the developed s-HA/PA composites in this study might be used for tissue engineering and bone repair.http://dx.doi.org/10.1155/2014/579252 |
| spellingShingle | Xuesong Zhang Ming Lu Yan Wang Xiaojing Su Xuelian Zhang The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials International Journal of Polymer Science |
| title | The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials |
| title_full | The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials |
| title_fullStr | The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials |
| title_full_unstemmed | The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials |
| title_short | The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials |
| title_sort | development of biomimetic spherical hydroxyapatite polyamide 66 biocomposites as bone repair materials |
| url | http://dx.doi.org/10.1155/2014/579252 |
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