Influence of Uterine Anomalies, Infection History, and Cervical Length on the Success of Cerclage in First-Time Pregnancies

Background: Cervical cerclage is an important procedure that helps keep pregnancies from ending prematurely in women with cervical weakness. So far, not much is known about how uterine abnormalities, infection background and cervical length affect the outcomes of cerclage surgery in first-time moth...

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Main Authors: Ayesha Saddiqa, Ayesha, Abeera Khalid, Nosheen Fatima, Hira Khalid, Syed Muntzir Mehdi, Pakeeza Shafique Ul Rehman
Format: Article
Language:English
Published: ziauddin University 2025-07-01
Series:Pakistan Journal of Medicine and Dentistry
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Online Access:https://ojs.zu.edu.pk/pjmd/article/view/3858
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Summary:Background: Cervical cerclage is an important procedure that helps keep pregnancies from ending prematurely in women with cervical weakness. So far, not much is known about how uterine abnormalities, infection background and cervical length affect the outcomes of cerclage surgery in first-time mothers. The aim of the study was to find out if uterine abnormalities, infection history and a short cervix influenced cerclage outcomes in single pregnancies. Methodology: A cross-sectional analytical study was performed at a specialized center with 80 pregnant women, 60 of whom had undergone cerclage and 20 who served as controls. Both detailed demographic, clinical and ultrasound data were thoroughly gathered. Associations were evaluated by using chi-square and t-tests. The main things looked at were a woman’s age, her BMI, the condition of her uterine structures, past history of infections, the length of the cervix and pregnancy results. Results: Average age among participants was 29.4 ± 4.2 years in the cerclage group and 28.9 ± 3.9 years in the control group (p = 0.52). The distributions of BMI and maternal age were very similar. Uterine irregularities were observed in nearly half (49.1%) of the women who had cerclage, contrasting with a 24.5% rate in the no-cerclage group (χ² = 4.27, p = 0.04). We found that infection history had a strong link (χ² = 4.14, p = 0.04). A cervical length of less than 2.5 centimeters was highly related to the decision to do a cerclage (χ² = 11.4, p = 0.001). Conclusion: The majority of cerclage failures occurred in women with uterine anomalies, but there was no link between the outcome and infection history (χ² = 0.01, p = 0.91). A positive result was seen between short cervical length and improved cerclage outcomes (χ² = 6.44, p = 0.01). Both the choice to do cerclage and the outcome depend greatly on uterine anomalies and a short cervix in primigravida women. Previous infections are taken into account for deciding a cerclage, but do not predict the outcome. Identifying issues in the uterus and cervix early can result in placing cerclages in the best place for the pregnancy.
ISSN:2313-7371
2308-2593