Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk
The high level of cadmium in the abdominal muscle of the brown shrimp <i>Crangon crangon</i> is due to the serious pollution of the water in the Gulf of Gdansk. The inhibition of malic enzyme (ME) activity by cadmium, and in consequence the reduced formation of NADPH, could interfere wit...
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| Format: | Article |
| Language: | English |
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Institute of Oceanology of the Polish Academy of Sciences
2011-09-01
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| Series: | Oceanologia |
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| Online Access: | http://www.iopan.gda.pl/oceanologia/53_3.html#A7 |
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| author | Edward F. Skorkowski Piotr Stepnowski Adriana Mika Anna Białk-Bielińska Natalia Niedźwiecka |
| author_facet | Edward F. Skorkowski Piotr Stepnowski Adriana Mika Anna Białk-Bielińska Natalia Niedźwiecka |
| author_sort | Edward F. Skorkowski |
| collection | DOAJ |
| description | The high level of cadmium in the abdominal muscle of the brown shrimp <i>Crangon crangon</i> is due to the serious pollution of the water in the Gulf of Gdansk. The inhibition of malic enzyme (ME) activity by cadmium, and in consequence the reduced formation of NADPH, could interfere with cellular mechanisms for detoxifying the organism and reducing oxidative stress. The reduced glutathione (GSH) concentration in the abdominal muscle of <it>C. crangon</it> was calculated to be 5.8 mM. The objective of this study was to evaluate the part played by GSH in the effect of cadmium on the activity of NADP-dependent malic enzyme from abdominal muscles of brown shrimps. This enzyme is activated by certain divalent cations (Mg, Mn). The results demonstrate that cadmium inhibits ME activity from shrimp muscle, and that GSH and albumin can reduce this cadmium-inhibited NADP-dependent malic enzyme activity. |
| format | Article |
| id | doaj-art-302feac5d22f42c7bc97daf62333fcb0 |
| institution | Kabale University |
| issn | 0078-3234 |
| language | English |
| publishDate | 2011-09-01 |
| publisher | Institute of Oceanology of the Polish Academy of Sciences |
| record_format | Article |
| series | Oceanologia |
| spelling | doaj-art-302feac5d22f42c7bc97daf62333fcb02025-08-20T03:49:07ZengInstitute of Oceanology of the Polish Academy of SciencesOceanologia0078-32342011-09-01533793805Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of GdańskEdward F. SkorkowskiPiotr StepnowskiAdriana MikaAnna Białk-BielińskaNatalia NiedźwieckaThe high level of cadmium in the abdominal muscle of the brown shrimp <i>Crangon crangon</i> is due to the serious pollution of the water in the Gulf of Gdansk. The inhibition of malic enzyme (ME) activity by cadmium, and in consequence the reduced formation of NADPH, could interfere with cellular mechanisms for detoxifying the organism and reducing oxidative stress. The reduced glutathione (GSH) concentration in the abdominal muscle of <it>C. crangon</it> was calculated to be 5.8 mM. The objective of this study was to evaluate the part played by GSH in the effect of cadmium on the activity of NADP-dependent malic enzyme from abdominal muscles of brown shrimps. This enzyme is activated by certain divalent cations (Mg, Mn). The results demonstrate that cadmium inhibits ME activity from shrimp muscle, and that GSH and albumin can reduce this cadmium-inhibited NADP-dependent malic enzyme activity.http://www.iopan.gda.pl/oceanologia/53_3.html#A7Gulf of GdańskShrimp<i>Crangon crangon</i>Abdomen muscleMalic enzymeCadmiumGlutathione |
| spellingShingle | Edward F. Skorkowski Piotr Stepnowski Adriana Mika Anna Białk-Bielińska Natalia Niedźwiecka Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk Oceanologia Gulf of Gdańsk Shrimp <i>Crangon crangon</i> Abdomen muscle Malic enzyme Cadmium Glutathione |
| title | Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk |
| title_full | Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk |
| title_fullStr | Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk |
| title_full_unstemmed | Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk |
| title_short | Effect of cadmium and glutathione on malic enzyme activity in brown shrimps (<i>Crangon crangon</i>) from the Gulf of Gdańsk |
| title_sort | effect of cadmium and glutathione on malic enzyme activity in brown shrimps i crangon crangon i from the gulf of gdansk |
| topic | Gulf of Gdańsk Shrimp <i>Crangon crangon</i> Abdomen muscle Malic enzyme Cadmium Glutathione |
| url | http://www.iopan.gda.pl/oceanologia/53_3.html#A7 |
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