POLYMORPHISM OF GENES OF IMMUNOSUPRESSIVE CYTOKINE IL-10 AND TGF-β AT TUBERCULOSIS INFECTION

POLYMORPHISM OF GENES OF IMMUNOSUPRESSIVE CYTOKINE IL-10 AND TGF-β AT TUBERCULOSIS INFECTION

The aim of the work was the study of connection of allelic polymorphism of IL10 and TGFВgenes with changes in the basal and BCG-induced production of immunosuppressive cytokines IL-10 and TGF-β by mononuclear leukocytes in vitro in patients with the first diagnosed pulmonary tuberculosis (TB), depen...

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Bibliographic Details
Main Authors: Ye. G. Churina, O. I. Urazova, V. V. Novitsky, O. V. Filinyuk
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2014-10-01
Series:Бюллетень сибирской медицины
Subjects:
gene polymorphism
cytokines
il-10
tgf-β
pulmonary tuberculosis
immune response
immune-suppression
Online Access:https://bulletin.ssmu.ru/jour/article/view/229
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