Statins and long-term risk of revision surgery after total hip arthroplasty in osteoarthritis: a multi-source data linkage study

Statins and long-term risk of revision surgery after total hip arthroplasty in osteoarthritis: a multi-source data linkage study

BackgroundStatins, widely used lipid lowering drugs, have been associated with pleiotropic beneficial effects. Notably, studies conducted in vitro and in vivo suggest a link between statins and bone metabolism. Observational data in humans also hint at a decreased fracture rate among statin users. R...

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Bibliographic Details
Main Authors: Andrea D'Amuri, Barbara Bordini, Mauro Pagani, Jacopo Ciaffi, Claudio D'Agostino, Alberto Di Martino, Cesare Faldini, Francesco Ursini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
osteoarthritis
statins
orthopedic surgery
total hip arthroplasty
prosthesis outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1492200/full
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