A pair of promising immune checkpoints PSGL-1 and VISTA from immunotolerance to immunotherapy

A pair of promising immune checkpoints PSGL-1 and VISTA from immunotolerance to immunotherapy

Abstract Immune checkpoints are crucial for regulating immune responses and maintaining self-tolerance, as they play a pivotal role in preventing autoimmunity and facilitating tumor immune evasion. This review concentrates on the immune checkpoint molecules PSGL-1 and VISTA. Both molecules are highl...

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Bibliographic Details
Main Authors: Manqing Peng, Xiaofang Lu, Junshuang Guo, Xiangli Yin, Jing Zhang, Xin Li, Yizhou Zou
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Biomarker Research
Subjects:
VISTA
PSGL-1
Cancer
Autoimmune diseases
Immune tolerance
Immunotherapy
Online Access:https://doi.org/10.1186/s40364-024-00693-8
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