ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient

Abstract Avian influenza A (H5N1) virus infection can cause severe pneumonia, but the development of acute respiratory distress syndrome (ARDS) and hemophagocytic lymphohistiocytosis (HLH) syndrome is rare. We report a case of rapidly progressive and fatal H5N1 infection that was complicated by HLH...

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Main Authors: Hamdy Ibrahim, Mohamed Saleh, Mohamed EL Sawy, Ahmed EL sisi, Ahmed Samir EL bahwashy, Abdel Rahman Eliwa, Youssef Eshak Naguib
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:The Egyptian Journal of Internal Medicine
Subjects:
Online Access:https://doi.org/10.1186/s43162-025-00490-1
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author Hamdy Ibrahim
Mohamed Saleh
Mohamed EL Sawy
Ahmed EL sisi
Ahmed Samir EL bahwashy
Abdel Rahman Eliwa
Youssef Eshak Naguib
author_facet Hamdy Ibrahim
Mohamed Saleh
Mohamed EL Sawy
Ahmed EL sisi
Ahmed Samir EL bahwashy
Abdel Rahman Eliwa
Youssef Eshak Naguib
author_sort Hamdy Ibrahim
collection DOAJ
description Abstract Avian influenza A (H5N1) virus infection can cause severe pneumonia, but the development of acute respiratory distress syndrome (ARDS) and hemophagocytic lymphohistiocytosis (HLH) syndrome is rare. We report a case of rapidly progressive and fatal H5N1 infection that was complicated by HLH and multiorgan failure. The purpose is to highlight the potential for H5N1 infection to trigger life-threatening complications, including ARDS and HLH syndrome. Early recognition and aggressive treatment may improve survival in these critically ill patients.
format Article
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institution Kabale University
issn 2090-9098
language English
publishDate 2025-07-01
publisher SpringerOpen
record_format Article
series The Egyptian Journal of Internal Medicine
spelling doaj-art-301eb818dcfb48e0a3e9fdc0087f247c2025-08-20T03:45:32ZengSpringerOpenThe Egyptian Journal of Internal Medicine2090-90982025-07-013711410.1186/s43162-025-00490-1ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patientHamdy Ibrahim0Mohamed Saleh1Mohamed EL Sawy2Ahmed EL sisi3Ahmed Samir EL bahwashy4Abdel Rahman Eliwa5Youssef Eshak Naguib6Ministry of Health and PopulationMinistry of Health and PopulationMinistry of Health and PopulationMinistry of Health and PopulationMinistry of Health and PopulationMinistry of Health and PopulationMinistry of Health and PopulationAbstract Avian influenza A (H5N1) virus infection can cause severe pneumonia, but the development of acute respiratory distress syndrome (ARDS) and hemophagocytic lymphohistiocytosis (HLH) syndrome is rare. We report a case of rapidly progressive and fatal H5N1 infection that was complicated by HLH and multiorgan failure. The purpose is to highlight the potential for H5N1 infection to trigger life-threatening complications, including ARDS and HLH syndrome. Early recognition and aggressive treatment may improve survival in these critically ill patients.https://doi.org/10.1186/s43162-025-00490-1Avian influenza (H5N1)ARDSHLH syndrome
spellingShingle Hamdy Ibrahim
Mohamed Saleh
Mohamed EL Sawy
Ahmed EL sisi
Ahmed Samir EL bahwashy
Abdel Rahman Eliwa
Youssef Eshak Naguib
ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient
The Egyptian Journal of Internal Medicine
Avian influenza (H5N1)
ARDS
HLH syndrome
title ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient
title_full ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient
title_fullStr ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient
title_full_unstemmed ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient
title_short ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient
title_sort ards and hlh syndromes induced by avian flu pneumonia in a farm worker patient
topic Avian influenza (H5N1)
ARDS
HLH syndrome
url https://doi.org/10.1186/s43162-025-00490-1
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