Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index

Changed lipid metabolic parameters in parallel with a blood loss volume were studied in patients with severe mechanical injury, which were comparable by the APACHE II scale severity. The study indicated the elevated levels of atherogenic fractions with the increased blood loss volume that was signif...

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Main Authors: L. N. Shcherbakova, A. A. Bessekeyev, L. V. Molchanova
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2006-12-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1360
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author L. N. Shcherbakova
A. A. Bessekeyev
L. V. Molchanova
author_facet L. N. Shcherbakova
A. A. Bessekeyev
L. V. Molchanova
author_sort L. N. Shcherbakova
collection DOAJ
description Changed lipid metabolic parameters in parallel with a blood loss volume were studied in patients with severe mechanical injury, which were comparable by the APACHE II scale severity. The study indicated the elevated levels of atherogenic fractions with the increased blood loss volume that was significantly pronounced when it was 37 ml/kg or more. A rise of the cholesterol atherogenicity index also occurred with the higher blood loss volume. Changes in the lipoprotein spectrum with a blood loss volume of 25 ml/kg or more preserve within a rehabilitative month. In severe mechanical injury, normalization of the lipid spectrum promotes the use of perfluorane. It is concluded that blood loss predominantly affects the lipoprotein spectrum in severe mechanical injury.
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publishDate 2006-12-01
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spelling doaj-art-301d2c878cab4fe3a80e61be0f1812382025-08-20T02:55:49ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-12-0126444910.15360/1813-9779-2006-6-44-491360Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity IndexL. N. Shcherbakova0A. A. Bessekeyev1L. V. Molchanova2Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowChanged lipid metabolic parameters in parallel with a blood loss volume were studied in patients with severe mechanical injury, which were comparable by the APACHE II scale severity. The study indicated the elevated levels of atherogenic fractions with the increased blood loss volume that was significantly pronounced when it was 37 ml/kg or more. A rise of the cholesterol atherogenicity index also occurred with the higher blood loss volume. Changes in the lipoprotein spectrum with a blood loss volume of 25 ml/kg or more preserve within a rehabilitative month. In severe mechanical injury, normalization of the lipid spectrum promotes the use of perfluorane. It is concluded that blood loss predominantly affects the lipoprotein spectrum in severe mechanical injury.https://www.reanimatology.com/rmt/article/view/1360severe mechanical injuryblood loss volumelipoprotein spectrum
spellingShingle L. N. Shcherbakova
A. A. Bessekeyev
L. V. Molchanova
Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index
Общая реаниматология
severe mechanical injury
blood loss volume
lipoprotein spectrum
title Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index
title_full Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index
title_fullStr Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index
title_full_unstemmed Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index
title_short Impact of Blood Loss Volume in Patients with Severe Mechanical Injury on the Cholesterol Atherogenicity Index
title_sort impact of blood loss volume in patients with severe mechanical injury on the cholesterol atherogenicity index
topic severe mechanical injury
blood loss volume
lipoprotein spectrum
url https://www.reanimatology.com/rmt/article/view/1360
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AT aabessekeyev impactofbloodlossvolumeinpatientswithseveremechanicalinjuryonthecholesterolatherogenicityindex
AT lvmolchanova impactofbloodlossvolumeinpatientswithseveremechanicalinjuryonthecholesterolatherogenicityindex