Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas
Introduction Colorectal carcinoma is the result of a series of mutations based on the adenoma-carcinoma sequence. We aimed to perform a comparative analysis of the immune expression of the parkin (PARK2 gene) and of the APC (APC gene) proteins in samples of colorectal polyps and aden...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2025-01-01
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| Series: | Brazilian Journal of Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1805086 |
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| author | William Augusto Casteleins Claudia Caroline Veloso da Silva-Camargo Amanda Pereira Agostinho Rosimeri Kuhl Svoboda Baldin Bruno Ribeiro Batista Jacqueline Nabhen Marcia Olandoski Lucia de Noronha Vanessa Santos Sotomaior |
| author_facet | William Augusto Casteleins Claudia Caroline Veloso da Silva-Camargo Amanda Pereira Agostinho Rosimeri Kuhl Svoboda Baldin Bruno Ribeiro Batista Jacqueline Nabhen Marcia Olandoski Lucia de Noronha Vanessa Santos Sotomaior |
| author_sort | William Augusto Casteleins |
| collection | DOAJ |
| description |
Introduction Colorectal carcinoma is the result of a series of mutations based on the adenoma-carcinoma sequence. We aimed to perform a comparative analysis of the immune expression of the parkin (PARK2 gene) and of the APC (APC gene) proteins in samples of colorectal polyps and adenocarcinomas. |
| format | Article |
| id | doaj-art-301ce400c8d9481f89a6740fbb30bbeb |
| institution | Kabale University |
| issn | 2526-8732 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Brazilian Journal of Oncology |
| spelling | doaj-art-301ce400c8d9481f89a6740fbb30bbeb2025-08-20T03:43:55ZengThieme Revinter Publicações Ltda.Brazilian Journal of Oncology2526-87322025-01-012110.1055/s-0045-1805086Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal AdenocarcinomasWilliam Augusto Casteleins0https://orcid.org/0000-0002-8728-5875Claudia Caroline Veloso da Silva-Camargo1https://orcid.org/0000-0001-7467-3679Amanda Pereira Agostinho2https://orcid.org/0000-0001-6909-3485Rosimeri Kuhl Svoboda Baldin3https://orcid.org/0000-0002-1308-3218Bruno Ribeiro Batista4https://orcid.org/0000-0002-6385-6821Jacqueline Nabhen5https://orcid.org/0000-0001-5655-6719Marcia Olandoski6https://orcid.org/0000-0002-0979-3604Lucia de Noronha7https://orcid.org/0000-0003-0310-7164Vanessa Santos Sotomaior8https://orcid.org/0000-0001-5388-6384Graduate Program in Health Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilAdvanced Molecular Investigation Group, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilAdvanced Molecular Investigation Group, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilAdvanced Molecular Investigation Group, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilGraduate Program in Health Technology, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilDepartment of Internal Medicine, Complexo do Hospital de Clínicas da Universidade Federal do Paraná, Curitiba, PR, BrazilGraduate Program in Health Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilGraduate Program in Health Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, PR, BrazilAdvanced Molecular Investigation Group, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil Introduction Colorectal carcinoma is the result of a series of mutations based on the adenoma-carcinoma sequence. We aimed to perform a comparative analysis of the immune expression of the parkin (PARK2 gene) and of the APC (APC gene) proteins in samples of colorectal polyps and adenocarcinomas.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1805086immunohistochemistryadenocarcinomaintestinal polypscolonrectumadenomatous polyposis coli |
| spellingShingle | William Augusto Casteleins Claudia Caroline Veloso da Silva-Camargo Amanda Pereira Agostinho Rosimeri Kuhl Svoboda Baldin Bruno Ribeiro Batista Jacqueline Nabhen Marcia Olandoski Lucia de Noronha Vanessa Santos Sotomaior Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas Brazilian Journal of Oncology immunohistochemistry adenocarcinoma intestinal polyps colon rectum adenomatous polyposis coli |
| title | Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas |
| title_full | Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas |
| title_fullStr | Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas |
| title_full_unstemmed | Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas |
| title_short | Comparative Analysis of the Immunohistochemical Expression of the Parkin and APC proteins in Polyps and Colorectal Adenocarcinomas |
| title_sort | comparative analysis of the immunohistochemical expression of the parkin and apc proteins in polyps and colorectal adenocarcinomas |
| topic | immunohistochemistry adenocarcinoma intestinal polyps colon rectum adenomatous polyposis coli |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1805086 |
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