Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups

Abstract Background Childhood-onset rheumatic diseases, such as juvenile idiopathic arthritis, juvenile-onset lupus and juvenile dermatomyositis, appear to be associated with an increased risk of comorbidities in adulthood compared to the general population. For the first stage of a research project...

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Main Authors: Sab Siddiq, Jenny Sammy Ainsworth, Clare E. Pain, Eve M.D. Smith, Sizheng Steven Zhao, David M. Hughes, Liza J. McCann
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Rheumatology
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Online Access:https://doi.org/10.1186/s41927-025-00492-0
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author Sab Siddiq
Jenny Sammy Ainsworth
Clare E. Pain
Eve M.D. Smith
Sizheng Steven Zhao
David M. Hughes
Liza J. McCann
author_facet Sab Siddiq
Jenny Sammy Ainsworth
Clare E. Pain
Eve M.D. Smith
Sizheng Steven Zhao
David M. Hughes
Liza J. McCann
author_sort Sab Siddiq
collection DOAJ
description Abstract Background Childhood-onset rheumatic diseases, such as juvenile idiopathic arthritis, juvenile-onset lupus and juvenile dermatomyositis, appear to be associated with an increased risk of comorbidities in adulthood compared to the general population. For the first stage of a research project evaluating this topic, we wanted to capture views from young people with juvenile-onset rheumatic disease to ensure that further work was relevant to their lived experience and priorities. This study aimed to determine (i) which comorbidities young people identify as important, (ii) how they access information about their disease, including comorbidity risk, whether (iii) they would like to hear about the risk of comorbidities whilst they are under paediatric care, and (iv) would be motivated to make lifestyle choices to decrease the risk of potential comorbidities. Methods A topic guide based on the proposed study aims was developed, and PowerPoint slides were prepared to facilitate three focus group discussions to gain insights from young people. Focus groups were conducted via video platform, and the views of young people were assimilated using notetaking and an online interactive polling tool. Results A total of 18 young people between 10 and 27 years of age participated in the focus groups. Mental health (including depression and anxiety) was described as important comorbidity by 17/18 (94%), followed by obesity or being overweight by 9/18 (50%), heart disease by 7/18 (39%) and stroke by 5/18 (28%) of participants. Young people reported searching United Kingdom National Health Service websites, charity resources, and Google for information on their disease and associated comorbidities. They stated that they would be willing to change their lifestyle to reduce the risk of comorbidities if information were given to them sensitively with clear practical steps for reducing risk. Conclusion Three groups of young people identified risk of mental health issues, obesity, and cardiovascular morbidities as particularly important to them. They reported searching online platforms related to their disease and increasingly accessed online resources as they transitioned from paediatric to adult care. Participants thought it would be helpful to provide information on young people’s disease and associated comorbidity in a motivational and sensitive way. Clinical trial number Not applicable.
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spelling doaj-art-301bbb0fafcf42dcbc347b0454f4e4742025-08-20T03:10:16ZengBMCBMC Rheumatology2520-10262025-04-01911910.1186/s41927-025-00492-0Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groupsSab Siddiq0Jenny Sammy Ainsworth1Clare E. Pain2Eve M.D. Smith3Sizheng Steven Zhao4David M. Hughes5Liza J. McCann6Department of Health Data Science, Institute of Population Health, University of LiverpoolInstitute of Life Course and Medical Sciences, University of LiverpoolDepartment of Paediatric Rheumatology, Institute in the Park, Alder Hey Children’s NHS Foundation TrustDepartment of Women and Children’s Health, Institute of Life Course and Medical Sciences, University of LiverpoolCentre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, School of Biological Sciences, Division of Musculoskeletal & Dermatological Sciences, University of ManchesterDepartment of Health Data Science, Institute of Population Health, University of LiverpoolDepartment of Paediatric Rheumatology, Institute in the Park, Alder Hey Children’s NHS Foundation TrustAbstract Background Childhood-onset rheumatic diseases, such as juvenile idiopathic arthritis, juvenile-onset lupus and juvenile dermatomyositis, appear to be associated with an increased risk of comorbidities in adulthood compared to the general population. For the first stage of a research project evaluating this topic, we wanted to capture views from young people with juvenile-onset rheumatic disease to ensure that further work was relevant to their lived experience and priorities. This study aimed to determine (i) which comorbidities young people identify as important, (ii) how they access information about their disease, including comorbidity risk, whether (iii) they would like to hear about the risk of comorbidities whilst they are under paediatric care, and (iv) would be motivated to make lifestyle choices to decrease the risk of potential comorbidities. Methods A topic guide based on the proposed study aims was developed, and PowerPoint slides were prepared to facilitate three focus group discussions to gain insights from young people. Focus groups were conducted via video platform, and the views of young people were assimilated using notetaking and an online interactive polling tool. Results A total of 18 young people between 10 and 27 years of age participated in the focus groups. Mental health (including depression and anxiety) was described as important comorbidity by 17/18 (94%), followed by obesity or being overweight by 9/18 (50%), heart disease by 7/18 (39%) and stroke by 5/18 (28%) of participants. Young people reported searching United Kingdom National Health Service websites, charity resources, and Google for information on their disease and associated comorbidities. They stated that they would be willing to change their lifestyle to reduce the risk of comorbidities if information were given to them sensitively with clear practical steps for reducing risk. Conclusion Three groups of young people identified risk of mental health issues, obesity, and cardiovascular morbidities as particularly important to them. They reported searching online platforms related to their disease and increasingly accessed online resources as they transitioned from paediatric to adult care. Participants thought it would be helpful to provide information on young people’s disease and associated comorbidity in a motivational and sensitive way. Clinical trial number Not applicable.https://doi.org/10.1186/s41927-025-00492-0Patient and public involvementFocus groupsJuvenile idiopathic arthritis – Juvenile-onset lupusJuvenile dermatomyositisComorbidityChildhood-onset
spellingShingle Sab Siddiq
Jenny Sammy Ainsworth
Clare E. Pain
Eve M.D. Smith
Sizheng Steven Zhao
David M. Hughes
Liza J. McCann
Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups
BMC Rheumatology
Patient and public involvement
Focus groups
Juvenile idiopathic arthritis – Juvenile-onset lupus
Juvenile dermatomyositis
Comorbidity
Childhood-onset
title Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups
title_full Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups
title_fullStr Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups
title_full_unstemmed Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups
title_short Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups
title_sort involving young people in research investigating comorbidity associated with childhood onset rheumatic disease perspectives of a series of focus groups
topic Patient and public involvement
Focus groups
Juvenile idiopathic arthritis – Juvenile-onset lupus
Juvenile dermatomyositis
Comorbidity
Childhood-onset
url https://doi.org/10.1186/s41927-025-00492-0
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