Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones
Objective: To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney stones. Methods: A retrospective, longitudinal, descriptive, and observational study was carried out by reviewing the hospital electronic medical record fro...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-07-01
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| Series: | Asian Journal of Urology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S221438822030059X |
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| author | Braulio Omar Manzo Jose David Cabrera Esteban Emiliani Hector Manuel Sánchez Brian Howard Eisner Jose Ernesto Torres |
| author_facet | Braulio Omar Manzo Jose David Cabrera Esteban Emiliani Hector Manuel Sánchez Brian Howard Eisner Jose Ernesto Torres |
| author_sort | Braulio Omar Manzo |
| collection | DOAJ |
| description | Objective: To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney stones. Methods: A retrospective, longitudinal, descriptive, and observational study was carried out by reviewing the hospital electronic medical record from 2014 to 2018. The adherence to drug treatment was measured 6 months after its initiation, and the numerical values of the metabolic studies were compared. Wilcoxon tests were performed to compare the difference before and after treatment. Results: Ninety patients were evaluated, with 73.3% of adherence. The 180-day overall adherence rate was 61.2% in patients treated with a single drug and 85.4% in patients treated with multiple drugs. There is a statistically significant increase in citrate levels in patients with good adherence in comparison with non-adherent patients (p=0.031 vs. p=0.528). Conclusions: Medical treatment and dietary measures in patients with kidney stones have an initial impact at 6 months on the values of the main urinary metabolic alterations that predispose to calculi formation; the most significant is seen in those patients with adherence to medical treatment for hypocitraturia. |
| format | Article |
| id | doaj-art-300e09de455b48979410ddc05dfa9aff |
| institution | OA Journals |
| issn | 2214-3882 |
| language | English |
| publishDate | 2021-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Urology |
| spelling | doaj-art-300e09de455b48979410ddc05dfa9aff2025-08-20T02:07:56ZengElsevierAsian Journal of Urology2214-38822021-07-018327527910.1016/j.ajur.2020.07.002Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stonesBraulio Omar Manzo0Jose David Cabrera1Esteban Emiliani2Hector Manuel Sánchez3Brian Howard Eisner4Jose Ernesto Torres5Urology Department, Hospital Regional de Alta Especialidad del Bajío, Blvd. Milenio #130, Col. San Carlos la Roncha, León, Guanajuato, Mexico; Corresponding author.Urology Department, Hospital Regional de Alta Especialidad del Bajío, Blvd. Milenio #130, Col. San Carlos la Roncha, León, Guanajuato, MexicoUrology Department, Fundación Puigvert, Universidad Autónoma de Barcelona, Barcelona, SpainUrology Department, Hospital Regional de Alta Especialidad del Bajío, Blvd. Milenio #130, Col. San Carlos la Roncha, León, Guanajuato, MexicoUrology Department, Massachusetts General Hospital, Harvard Medical School, Boston, USAUrology Department, Hospital Regional de Alta Especialidad del Bajío, Blvd. Milenio #130, Col. San Carlos la Roncha, León, Guanajuato, MexicoObjective: To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney stones. Methods: A retrospective, longitudinal, descriptive, and observational study was carried out by reviewing the hospital electronic medical record from 2014 to 2018. The adherence to drug treatment was measured 6 months after its initiation, and the numerical values of the metabolic studies were compared. Wilcoxon tests were performed to compare the difference before and after treatment. Results: Ninety patients were evaluated, with 73.3% of adherence. The 180-day overall adherence rate was 61.2% in patients treated with a single drug and 85.4% in patients treated with multiple drugs. There is a statistically significant increase in citrate levels in patients with good adherence in comparison with non-adherent patients (p=0.031 vs. p=0.528). Conclusions: Medical treatment and dietary measures in patients with kidney stones have an initial impact at 6 months on the values of the main urinary metabolic alterations that predispose to calculi formation; the most significant is seen in those patients with adherence to medical treatment for hypocitraturia.http://www.sciencedirect.com/science/article/pii/S221438822030059XKidney stonesRenal stonesMetabolic disordersMedical treatmentCitrateOxalate |
| spellingShingle | Braulio Omar Manzo Jose David Cabrera Esteban Emiliani Hector Manuel Sánchez Brian Howard Eisner Jose Ernesto Torres Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones Asian Journal of Urology Kidney stones Renal stones Metabolic disorders Medical treatment Citrate Oxalate |
| title | Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones |
| title_full | Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones |
| title_fullStr | Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones |
| title_full_unstemmed | Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones |
| title_short | Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones |
| title_sort | impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones |
| topic | Kidney stones Renal stones Metabolic disorders Medical treatment Citrate Oxalate |
| url | http://www.sciencedirect.com/science/article/pii/S221438822030059X |
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