Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries
Introduction: Palliative radiotherapy is essential for managing bone metastases, providing effective pain relief, and improving quality of life. While multiple fractions of radiotherapy are commonly used in high-income countries, randomized studies have established single-fraction palliative radioth...
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| Language: | English |
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Mary Ann Liebert
2025-01-01
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| Series: | Palliative Medicine Reports |
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| Online Access: | https://www.liebertpub.com/doi/10.1089/pmr.2024.0085 |
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| author | Erika Galietta Costanza M. Donati Maria Vadala’ Francesco Cellini Von Kaganda Bomboka Romina Rossi Milly Buwenge Tigeneh Wondemagegnehu Biniyam Tefera Deressa A.F.M. Kamal Uddin Mostafa A. Sumon Marco Maltoni Alessio G. Morganti |
| author_facet | Erika Galietta Costanza M. Donati Maria Vadala’ Francesco Cellini Von Kaganda Bomboka Romina Rossi Milly Buwenge Tigeneh Wondemagegnehu Biniyam Tefera Deressa A.F.M. Kamal Uddin Mostafa A. Sumon Marco Maltoni Alessio G. Morganti |
| author_sort | Erika Galietta |
| collection | DOAJ |
| description | Introduction: Palliative radiotherapy is essential for managing bone metastases, providing effective pain relief, and improving quality of life. While multiple fractions of radiotherapy are commonly used in high-income countries, randomized studies have established single-fraction palliative radiotherapy as an equally effective standard for uncomplicated painful bone metastases. Despite its proven effectiveness, there is still some reluctance to adopt single-fraction palliative radiotherapy in high-income countries. In low- and middle-income countries, single-fraction palliative radiotherapy can address many challenges, such as limited resources and difficulties in delivering cancer care, by reducing the number of treatment sessions and improving patient accessibility. However, barriers to single-fraction palliative radiotherapy adoption in low- and middle-income countries remain. Materials and Methods: This narrative review examines the barriers to single-fraction palliative radiotherapy adoption for bone metastases in low- and middle-income countries and explores possible solutions. Results: It highlights the effectiveness and benefits of single-fraction palliative radiotherapy in resource-limited settings and emphasizes the need for a tailored approach that includes policy development, clinical guidelines, training, research, and community engagement. Conclusions: Ultimately, this collaborative effort can improve palliative care and patient outcomes, regardless of location or economic conditions. |
| format | Article |
| id | doaj-art-30025aae3a9849af8a2437d23e53573f |
| institution | DOAJ |
| issn | 2689-2820 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Mary Ann Liebert |
| record_format | Article |
| series | Palliative Medicine Reports |
| spelling | doaj-art-30025aae3a9849af8a2437d23e53573f2025-08-20T02:59:07ZengMary Ann LiebertPalliative Medicine Reports2689-28202025-01-016112212810.1089/pmr.2024.0085Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income CountriesErika Galietta0Costanza M. Donati1Maria Vadala’2Francesco Cellini3Von Kaganda Bomboka4Romina Rossi5Milly Buwenge6Tigeneh Wondemagegnehu7Biniyam Tefera Deressa8A.F.M. Kamal Uddin9Mostafa A. Sumon10Marco Maltoni11Alessio G. Morganti12Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC di Radioterapia, Roma, Italy.Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum—Bologna University, Bologna, Italy.Radiotherapy Department, IRCCS Istituto Romagnolo per lo Studio dei Tumori “Dino Amadori” (IRST), Meldola, Italy.Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum—Bologna University, Bologna, Italy.Radiotherapy Department, Department of Clinical Oncology, College of Medicine and Health Sciences, Tikur Anbessa Specialized Hospital, University of Gondar, Addis Ababa, Ethiopia.Oncology Department, Adama Hospital Medical College, Adama, Ethiopia.Department of Radiation Oncology National Institute of ENT & Scientific Secretary Oncology Club, Dhaka, Bangladesh.Radiation Oncology, Kurmitola General Hospital, Dhaka, Bangladesh.Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum—Bologna University, Bologna, Italy.Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.Introduction: Palliative radiotherapy is essential for managing bone metastases, providing effective pain relief, and improving quality of life. While multiple fractions of radiotherapy are commonly used in high-income countries, randomized studies have established single-fraction palliative radiotherapy as an equally effective standard for uncomplicated painful bone metastases. Despite its proven effectiveness, there is still some reluctance to adopt single-fraction palliative radiotherapy in high-income countries. In low- and middle-income countries, single-fraction palliative radiotherapy can address many challenges, such as limited resources and difficulties in delivering cancer care, by reducing the number of treatment sessions and improving patient accessibility. However, barriers to single-fraction palliative radiotherapy adoption in low- and middle-income countries remain. Materials and Methods: This narrative review examines the barriers to single-fraction palliative radiotherapy adoption for bone metastases in low- and middle-income countries and explores possible solutions. Results: It highlights the effectiveness and benefits of single-fraction palliative radiotherapy in resource-limited settings and emphasizes the need for a tailored approach that includes policy development, clinical guidelines, training, research, and community engagement. Conclusions: Ultimately, this collaborative effort can improve palliative care and patient outcomes, regardless of location or economic conditions.https://www.liebertpub.com/doi/10.1089/pmr.2024.0085bone metastasesfractionationlow-resourced settingsnarrative reviewpain reliefpalliative radiotherapy |
| spellingShingle | Erika Galietta Costanza M. Donati Maria Vadala’ Francesco Cellini Von Kaganda Bomboka Romina Rossi Milly Buwenge Tigeneh Wondemagegnehu Biniyam Tefera Deressa A.F.M. Kamal Uddin Mostafa A. Sumon Marco Maltoni Alessio G. Morganti Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries Palliative Medicine Reports bone metastases fractionation low-resourced settings narrative review pain relief palliative radiotherapy |
| title | Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries |
| title_full | Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries |
| title_fullStr | Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries |
| title_full_unstemmed | Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries |
| title_short | Breaking Barriers to Better Care: A Narrative Review on the Adoption of Single-Fraction Palliative Radiotherapy for Bone Metastases in Low- and Middle-Income Countries |
| title_sort | breaking barriers to better care a narrative review on the adoption of single fraction palliative radiotherapy for bone metastases in low and middle income countries |
| topic | bone metastases fractionation low-resourced settings narrative review pain relief palliative radiotherapy |
| url | https://www.liebertpub.com/doi/10.1089/pmr.2024.0085 |
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