Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)

The plant hormone ethylene elicits crucial regulatory effects on plant growth, development, and stress resistance. As the enzyme that catalyzes the final step of ethylene biosynthesis, 1-Aminocyclopropane-1-carboxylic acid oxidase (ACO) plays a key role in precisely controlling ethylene production....

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Main Authors: Jing Xia, Yingsheng Qiu, Wanli Li, Yingcheng Zhang, Linxin Liu, Yi Wang, Wangshu Mou, Dawei Xue
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Plants
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Online Access:https://www.mdpi.com/2223-7747/13/24/3490
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author Jing Xia
Yingsheng Qiu
Wanli Li
Yingcheng Zhang
Linxin Liu
Yi Wang
Wangshu Mou
Dawei Xue
author_facet Jing Xia
Yingsheng Qiu
Wanli Li
Yingcheng Zhang
Linxin Liu
Yi Wang
Wangshu Mou
Dawei Xue
author_sort Jing Xia
collection DOAJ
description The plant hormone ethylene elicits crucial regulatory effects on plant growth, development, and stress resistance. As the enzyme that catalyzes the final step of ethylene biosynthesis, 1-Aminocyclopropane-1-carboxylic acid oxidase (ACO) plays a key role in precisely controlling ethylene production. However, the functional characterization of the <i>ACO</i> gene family in rice remains largely unexplored. In this study, we performed a phylogenetic analysis of seven <i>OsACO</i> genes (<i>OsACO1</i>–<i>OsACO7</i>), which were classified into three subfamilies (Types I, II, and III). The members within the same clades exhibited similar tertiary structures and conserved protein motifs. We conducted inter/intraspecies covariance assays of OsACOs to elucidate their evolutionary and duplication events. Numerous cis-acting elements identified in <i>OsACO</i> promoter regions are associated with development, hormonal stimuli, and environmental responses. The expression assay by RT-qPCR revealed that <i>OsACO</i> genes exhibited tissue-specific expression and were significantly altered under various abiotic stresses, indicating their potential involvement in these processes regulated at the transcriptional level. Additionally, we predicted candidate-targeting miRNAs and identified putative cysteine sites of S-nitrosylation (SNO) and S-sulfhydration (SSH) in OsACOs, providing insights into their post-transcriptional and post-translational regulatory mechanisms. These findings pave the way for the further investigation of OsACO functions and their potential applications in improving rice growth and stress resilience by modulating ethylene biosynthesis.
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spelling doaj-art-2ff7200a9a0f487ba1b7f8b9da2e88122025-08-20T02:56:58ZengMDPI AGPlants2223-77472024-12-011324349010.3390/plants13243490Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)Jing Xia0Yingsheng Qiu1Wanli Li2Yingcheng Zhang3Linxin Liu4Yi Wang5Wangshu Mou6Dawei Xue7College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaThe plant hormone ethylene elicits crucial regulatory effects on plant growth, development, and stress resistance. As the enzyme that catalyzes the final step of ethylene biosynthesis, 1-Aminocyclopropane-1-carboxylic acid oxidase (ACO) plays a key role in precisely controlling ethylene production. However, the functional characterization of the <i>ACO</i> gene family in rice remains largely unexplored. In this study, we performed a phylogenetic analysis of seven <i>OsACO</i> genes (<i>OsACO1</i>–<i>OsACO7</i>), which were classified into three subfamilies (Types I, II, and III). The members within the same clades exhibited similar tertiary structures and conserved protein motifs. We conducted inter/intraspecies covariance assays of OsACOs to elucidate their evolutionary and duplication events. Numerous cis-acting elements identified in <i>OsACO</i> promoter regions are associated with development, hormonal stimuli, and environmental responses. The expression assay by RT-qPCR revealed that <i>OsACO</i> genes exhibited tissue-specific expression and were significantly altered under various abiotic stresses, indicating their potential involvement in these processes regulated at the transcriptional level. Additionally, we predicted candidate-targeting miRNAs and identified putative cysteine sites of S-nitrosylation (SNO) and S-sulfhydration (SSH) in OsACOs, providing insights into their post-transcriptional and post-translational regulatory mechanisms. These findings pave the way for the further investigation of OsACO functions and their potential applications in improving rice growth and stress resilience by modulating ethylene biosynthesis.https://www.mdpi.com/2223-7747/13/24/34901-Aminocyclopropane-1-carboxylic acid oxidase (ACO)ethylene biosynthesisricetranscriptional regulationpost-translational modificationabiotic stress
spellingShingle Jing Xia
Yingsheng Qiu
Wanli Li
Yingcheng Zhang
Linxin Liu
Yi Wang
Wangshu Mou
Dawei Xue
Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)
Plants
1-Aminocyclopropane-1-carboxylic acid oxidase (ACO)
ethylene biosynthesis
rice
transcriptional regulation
post-translational modification
abiotic stress
title Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)
title_full Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)
title_fullStr Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)
title_full_unstemmed Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)
title_short Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (<i>Oryza sativa</i> L.)
title_sort genome wide in silico analysis of 1 aminocyclopropane 1 carboxylate oxidase aco gene family in rice i oryza sativa i l
topic 1-Aminocyclopropane-1-carboxylic acid oxidase (ACO)
ethylene biosynthesis
rice
transcriptional regulation
post-translational modification
abiotic stress
url https://www.mdpi.com/2223-7747/13/24/3490
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