A Case of Priapism with Risperidone

Priapism is a urologic emergency defined as a prolonged, possibly painful, penile erection. There are several known causes of priapism including psychotropic medications. One of the mechanisms by which antipsychotics are believed to induce priapism is through alpha-1 antagonism. This is case of a 50...

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Main Authors: Almari Ginory, Mathew Nguyen
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2014/241573
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author Almari Ginory
Mathew Nguyen
author_facet Almari Ginory
Mathew Nguyen
author_sort Almari Ginory
collection DOAJ
description Priapism is a urologic emergency defined as a prolonged, possibly painful, penile erection. There are several known causes of priapism including psychotropic medications. One of the mechanisms by which antipsychotics are believed to induce priapism is through alpha-1 antagonism. This is case of a 50-year-old male with a history of schizophrenia with previous priapism related to trazodone, who presents with new onset priapism associated with risperidone. In this case, the treatment of priapism includes discontinuation of the offending agent and drainage of the corpus cavernosum twice along with intracavernosal phenylephrine injections. It is important to educate patients on priapism as a possible side effect of medications. It is also important to consider previous episodes of medication-induced priapism when prescribing psychotropic medications as this may increase the patient’s future risk of priapism.
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spelling doaj-art-2ff33d34eb4e4c34b58d8947781807bd2025-08-20T02:07:56ZengWileyCase Reports in Psychiatry2090-682X2090-68382014-01-01201410.1155/2014/241573241573A Case of Priapism with RisperidoneAlmari Ginory0Mathew Nguyen1Department of Psychiatry, University of Florida, Gainesville, FL 32610, USADepartment of Psychiatry, University of Florida, Gainesville, FL 32610, USAPriapism is a urologic emergency defined as a prolonged, possibly painful, penile erection. There are several known causes of priapism including psychotropic medications. One of the mechanisms by which antipsychotics are believed to induce priapism is through alpha-1 antagonism. This is case of a 50-year-old male with a history of schizophrenia with previous priapism related to trazodone, who presents with new onset priapism associated with risperidone. In this case, the treatment of priapism includes discontinuation of the offending agent and drainage of the corpus cavernosum twice along with intracavernosal phenylephrine injections. It is important to educate patients on priapism as a possible side effect of medications. It is also important to consider previous episodes of medication-induced priapism when prescribing psychotropic medications as this may increase the patient’s future risk of priapism.http://dx.doi.org/10.1155/2014/241573
spellingShingle Almari Ginory
Mathew Nguyen
A Case of Priapism with Risperidone
Case Reports in Psychiatry
title A Case of Priapism with Risperidone
title_full A Case of Priapism with Risperidone
title_fullStr A Case of Priapism with Risperidone
title_full_unstemmed A Case of Priapism with Risperidone
title_short A Case of Priapism with Risperidone
title_sort case of priapism with risperidone
url http://dx.doi.org/10.1155/2014/241573
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