TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosis

TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosis

Abstract Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer, and ranks among the most lethal malignancies globally, primarily due to its high rates of recurrence and metastasis. Despite the urgency, no reliable biomarkers currently exist for predicting tumor recurrence in HCC....

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Bibliographic Details
Main Authors: Jin Li, Ling Bai, Zhaodan Xin, Jiajia Song, Hao Chen, Xingbo Song, Juan Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
HCC
TERT promoter mutation
TP53 mutation
Recurrence
Prognosis
Online Access:https://doi.org/10.1038/s41598-025-87545-z
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