Genetic evidence for the liver-brain axis: lipid metabolism and neurodegenerative disease risk
Abstract Background The liver‒brain axis is critical in neurodegenerative diseases (NDs), with lipid metabolism influencing neuroinflammation and microglial function. A systematic investigation of the genetic relationship between lipid metabolism abnormalities and ND, namely, Alzheimer's diseas...
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Main Authors: | Zeyu Wang, Zixiao Yin, Guangyong Sun, Dong Zhang, Jianguo Zhang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Lipids in Health and Disease |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12944-025-02455-3 |
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