Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma

Since 1986, the simultaneous presence of an hematologic malignancy and sarcoidosis, defined as sarcoidosis-lymphoma syndrome (SLS), has been described in 79 patients. The majority of these patients were affected by sarcoidosis and developed, after one or two years, a non-Hodgkin Lymphoma or an acute...

Full description

Saved in:
Bibliographic Details
Main Authors: Martina Torchio, Giorgio Bottaro, Giampiera Bertolino, Giuditta Comolli, Barbara Dal Bello, Rosangela Invernizzi, Marco Danova
Format: Article
Language:English
Published: PAGEPress Publications 2014-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:https://mjhid.org/index.php/mjhid/article/view/1838
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850215924846559232
author Martina Torchio
Giorgio Bottaro
Giampiera Bertolino
Giuditta Comolli
Barbara Dal Bello
Rosangela Invernizzi
Marco Danova
author_facet Martina Torchio
Giorgio Bottaro
Giampiera Bertolino
Giuditta Comolli
Barbara Dal Bello
Rosangela Invernizzi
Marco Danova
author_sort Martina Torchio
collection DOAJ
description Since 1986, the simultaneous presence of an hematologic malignancy and sarcoidosis, defined as sarcoidosis-lymphoma syndrome (SLS), has been described in 79 patients. The majority of these patients were affected by sarcoidosis and developed, after one or two years, a non-Hodgkin Lymphoma or an acute leukemia, while in only less than twenty cases the malignancy came first. In this report we describe the case of a 83 year old man with a clinical history of gastric mucosa-associated lymphoma (MALT), which was Helicobacter pylori-positive. He developed sarcoidosis ten years after the first diagnosis. The late onset of sarcoidosis in our patient made the diagnostic work-up and differential diagnosis between a lymphoma relapse and a de novo sarcoidosis extremely challenging.
format Article
id doaj-art-2fe9b86a9cf3440a99e6f806a58f1b28
institution OA Journals
issn 2035-3006
language English
publishDate 2014-08-01
publisher PAGEPress Publications
record_format Article
series Mediterranean Journal of Hematology and Infectious Diseases
spelling doaj-art-2fe9b86a9cf3440a99e6f806a58f1b282025-08-20T02:08:27ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphomaMartina Torchio0Giorgio Bottaro1Giampiera Bertolino2Giuditta Comolli3Barbara Dal Bello4Rosangela Invernizzi5Marco Danova6Internal Medicine and Medical Oncology Department, Ospedale Civile di Vigevano, Azienda Ospedaliera della Provincia di Pavia, Vigevano (Pavia)Internal Medicine and Medical Oncology Department, Ospedale Civile di Vigevano, Azienda Ospedaliera della Provincia di Pavia, Vigevano (Pavia)Istituto di Clinica Medica III Università di Pavia e Fondazione IRCCS San Matteo, Pavia.Laboratori Sperimentali di Ricerca Area Biotecnologie e S.C. di Microbiologia e Virologia, Fondazione IRCCS San Matteo, Pavia.Dipartimento di Anatomia Patologica Università di Pavia, Pavia.The author declare that they co competing interests exist.Internal Medicine and Medical Oncology Department, Ospedale Civile di Vigevano, Azienda Ospedaliera della Provincia di Pavia, Vigevano (Pavia)Since 1986, the simultaneous presence of an hematologic malignancy and sarcoidosis, defined as sarcoidosis-lymphoma syndrome (SLS), has been described in 79 patients. The majority of these patients were affected by sarcoidosis and developed, after one or two years, a non-Hodgkin Lymphoma or an acute leukemia, while in only less than twenty cases the malignancy came first. In this report we describe the case of a 83 year old man with a clinical history of gastric mucosa-associated lymphoma (MALT), which was Helicobacter pylori-positive. He developed sarcoidosis ten years after the first diagnosis. The late onset of sarcoidosis in our patient made the diagnostic work-up and differential diagnosis between a lymphoma relapse and a de novo sarcoidosis extremely challenging.https://mjhid.org/index.php/mjhid/article/view/1838MALT lymphomasarcoidosisSarcoidosis-lymphoma syndrome
spellingShingle Martina Torchio
Giorgio Bottaro
Giampiera Bertolino
Giuditta Comolli
Barbara Dal Bello
Rosangela Invernizzi
Marco Danova
Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma
Mediterranean Journal of Hematology and Infectious Diseases
MALT lymphoma
sarcoidosis
Sarcoidosis-lymphoma syndrome
title Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma
title_full Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma
title_fullStr Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma
title_full_unstemmed Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma
title_short Late onset of sarcoidosis in a patient with gastric MALT non-Hodgkin lymphoma
title_sort late onset of sarcoidosis in a patient with gastric malt non hodgkin lymphoma
topic MALT lymphoma
sarcoidosis
Sarcoidosis-lymphoma syndrome
url https://mjhid.org/index.php/mjhid/article/view/1838
work_keys_str_mv AT martinatorchio lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma
AT giorgiobottaro lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma
AT giampierabertolino lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma
AT giudittacomolli lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma
AT barbaradalbello lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma
AT rosangelainvernizzi lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma
AT marcodanova lateonsetofsarcoidosisinapatientwithgastricmaltnonhodgkinlymphoma