MUTATION ANALYSIS FOR NUCLEOPHOSMIN-1 (NPM1) GENE VARIANT OF CHRONIC MYELOID LEUKEMIA PATIENTS FROM LAHORE-PAKISTAN

MUTATION ANALYSIS FOR NUCLEOPHOSMIN-1 (NPM1) GENE VARIANT OF CHRONIC MYELOID LEUKEMIA PATIENTS FROM LAHORE-PAKISTAN

Background: Chronic Myeloid Leukemia (CML) is a malignant genetic disorder commonly caused by the translocation of two genes among chromosomes 9 and 22. Nucleophosmin1 (NPM1) is a nuclear protein-coded gene located on chromosome 5q35. NPM1 protein, in association with other tumor suppressor protein...

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Bibliographic Details
Main Authors: Sumaira Mehboob, Kokab Durri, Muhammad Farooq Sabar, Hira Muzzamal, Farkhanda Manzoor
Format: Article
Language:English
Published: Superior University Lahore, Pakistan 2025-03-01
Series:International Journal of Pharmacy & Integrated Health Sciences
Subjects:
Leukemia
Chronic myeloid leukemia (CML)
Nucleophosmin-1 protein
NPM1 mutations
Gene sequencing.
Online Access:https://ijpihs.pk/index.php/IJPIHS/article/view/196
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