Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation

<b>Objectives:</b> Dental caries remains a prevalent issue in pediatric dentistry, necessitating restorative materials that not only repair decay but also provide protective benefits. Fluoride-releasing restorative materials have a key function in preventing recurrent caries by inhibitin...

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Main Authors: Angelo Aliberti, Roberta Gasparro, Maria Triassi, Mirko Piscopo, Pietro Ausiello, João Paulo Mendes Tribst
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Dentistry Journal
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Online Access:https://www.mdpi.com/2304-6767/13/5/224
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author Angelo Aliberti
Roberta Gasparro
Maria Triassi
Mirko Piscopo
Pietro Ausiello
João Paulo Mendes Tribst
author_facet Angelo Aliberti
Roberta Gasparro
Maria Triassi
Mirko Piscopo
Pietro Ausiello
João Paulo Mendes Tribst
author_sort Angelo Aliberti
collection DOAJ
description <b>Objectives:</b> Dental caries remains a prevalent issue in pediatric dentistry, necessitating restorative materials that not only repair decay but also provide protective benefits. Fluoride-releasing restorative materials have a key function in preventing recurrent caries by inhibiting bacterial activity and promoting remineralization. The objective of this study was to examine fluoride release from three pediatric dental restorative materials—<i>Riva Light Cure HV</i>, <i>Fuji IX GP Fast</i>, and the <i>Cention Forte Filling Material</i>—under different pH and temperature conditions. <b>Methods</b>: Specimens (10 mm diameter and 2 mm thickness; n = 3 for each material) were prepared according to the manufacturers’ instructions; immersed in buffer solutions at pH 4.8, 6.8, and 8.8; and stored at 37 °C and 44 °C. Fluoride release was quantified using ion chromatography at three time points (1 day, 7 days, and 28 days). <b>Results</b>: The data revealed that fluoride release was significantly influenced by pH, temperature, and time (<i>p</i> < 0.05). <i>Riva Light Cure HV</i> exhibited the highest release, particularly in acidic conditions (pH 4.8), reaching 40.14 mg/L at 44 °C after 28 days. The <i>Cention Forte Filling Material</i> and <i>Fuji IX GP Fast</i> also showed increased release over time, but with lower cumulative concentrations. Higher temperatures generally enhanced fluoride diffusion across all materials. <b>Conclusions</b>: These findings emphasize the pivotal impact of environmental factors in fluoride release dynamics. <i>Riva Light Cure HV</i> demonstrated superior fluoride release, particularly in acidic environments, suggesting its potential for high-caries-risk pediatric patients. These insights can inform the selection of restorative materials in pediatric dentistry, optimizing caries prevention strategies.
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spelling doaj-art-2fe6a7f0244841e0a81c6e205bebe37e2025-08-20T02:33:55ZengMDPI AGDentistry Journal2304-67672025-05-0113522410.3390/dj13050224Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory InvestigationAngelo Aliberti0Roberta Gasparro1Maria Triassi2Mirko Piscopo3Pietro Ausiello4João Paulo Mendes Tribst5Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, ItalyInterdepartmental Research Centre in Health Management and Innovation in Healthcare (CIRMIS), Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Reconstructive Oral Care, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit Amsterdam, 1081 Amsterdam, The Netherlands<b>Objectives:</b> Dental caries remains a prevalent issue in pediatric dentistry, necessitating restorative materials that not only repair decay but also provide protective benefits. Fluoride-releasing restorative materials have a key function in preventing recurrent caries by inhibiting bacterial activity and promoting remineralization. The objective of this study was to examine fluoride release from three pediatric dental restorative materials—<i>Riva Light Cure HV</i>, <i>Fuji IX GP Fast</i>, and the <i>Cention Forte Filling Material</i>—under different pH and temperature conditions. <b>Methods</b>: Specimens (10 mm diameter and 2 mm thickness; n = 3 for each material) were prepared according to the manufacturers’ instructions; immersed in buffer solutions at pH 4.8, 6.8, and 8.8; and stored at 37 °C and 44 °C. Fluoride release was quantified using ion chromatography at three time points (1 day, 7 days, and 28 days). <b>Results</b>: The data revealed that fluoride release was significantly influenced by pH, temperature, and time (<i>p</i> < 0.05). <i>Riva Light Cure HV</i> exhibited the highest release, particularly in acidic conditions (pH 4.8), reaching 40.14 mg/L at 44 °C after 28 days. The <i>Cention Forte Filling Material</i> and <i>Fuji IX GP Fast</i> also showed increased release over time, but with lower cumulative concentrations. Higher temperatures generally enhanced fluoride diffusion across all materials. <b>Conclusions</b>: These findings emphasize the pivotal impact of environmental factors in fluoride release dynamics. <i>Riva Light Cure HV</i> demonstrated superior fluoride release, particularly in acidic environments, suggesting its potential for high-caries-risk pediatric patients. These insights can inform the selection of restorative materials in pediatric dentistry, optimizing caries prevention strategies.https://www.mdpi.com/2304-6767/13/5/224fluorideglass ionomer cementspediatric dentistrydental materialspreventive dentistryions
spellingShingle Angelo Aliberti
Roberta Gasparro
Maria Triassi
Mirko Piscopo
Pietro Ausiello
João Paulo Mendes Tribst
Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation
Dentistry Journal
fluoride
glass ionomer cements
pediatric dentistry
dental materials
preventive dentistry
ions
title Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation
title_full Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation
title_fullStr Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation
title_full_unstemmed Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation
title_short Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation
title_sort fluoride release from pediatric dental restorative materials a laboratory investigation
topic fluoride
glass ionomer cements
pediatric dentistry
dental materials
preventive dentistry
ions
url https://www.mdpi.com/2304-6767/13/5/224
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AT mariatriassi fluoridereleasefrompediatricdentalrestorativematerialsalaboratoryinvestigation
AT mirkopiscopo fluoridereleasefrompediatricdentalrestorativematerialsalaboratoryinvestigation
AT pietroausiello fluoridereleasefrompediatricdentalrestorativematerialsalaboratoryinvestigation
AT joaopaulomendestribst fluoridereleasefrompediatricdentalrestorativematerialsalaboratoryinvestigation