High-resolution esophageal manometry in patients with achalasia
Introduction. At present, high-resolution esophageal manometry is the «gold standard» for the diagnosis of esophageal achalasia, based on the determination of the integrated relaxation pressure of the lower esophageal sphincter, the value of which in the case of achalasia must exceed 15 mm Hg (MMS S...
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Pavlov First Saint Petersburg State Medical University
2021-06-01
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| Series: | Вестник хирургии имени И.И. Грекова |
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| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/1777 |
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| author | A. A. Smirnov M. M. Kiriltseva M. E. Luybchenko L. I. Davletbaeva A. V. Kochetkov |
| author_facet | A. A. Smirnov M. M. Kiriltseva M. E. Luybchenko L. I. Davletbaeva A. V. Kochetkov |
| author_sort | A. A. Smirnov |
| collection | DOAJ |
| description | Introduction. At present, high-resolution esophageal manometry is the «gold standard» for the diagnosis of esophageal achalasia, based on the determination of the integrated relaxation pressure of the lower esophageal sphincter, the value of which in the case of achalasia must exceed 15 mm Hg (MMS System). However, in some patients with clinically and radiologically confirmed achalasia, this value is normal. There is no unified view of the cause of this phenomenon. We assumed that low pressure figures may be affected by incorrect installation of the manometric catheter.Methods and materials. This research included 149 patients (61 by retrospective estimating the patients data and 88 new patients) with achalasia established during the period from January 2017 to March 2020. When it was impossible to localize the lower esophageal sphincter and take correct measurements during high-resolution manometry in new patients, the X-rays or upper endoscopy was performed to control the manometric catheter placement. If its’ placement was incorrect and the integrated relaxation pressure level was lower than 15 mmHg, repeated high-resolution manometry was performed with the over-the-guidewire manometric catheter placing.Results. In 36 patients of both groups (24.2 %), the manometric data did not correspond to esophageal achalasia; in the prospective group, 12 out of the 19 patients had incorrect manometric data due to inability to visualize lower esophageal sphincter. In the prospective group, the manometric catheter was reinstalled by a guidewire, which allowed visualizing the signs of the lower esophageal sphincter in all cases, and in 15 out of 19 patients (79 %), the integrated relaxation pressure of the lower esophageal sphincter was more than 15 mm Hg.Conclusions. In some cases, the over-the-guidewire installing makes it possible to pass catheter through the lower esophageal sphincter correctly, visualize the lower esophageal sphincter during the high-resolution manometry examination and obtain true pressure values. |
| format | Article |
| id | doaj-art-2fe2a26a9b514c2cab8392db65da2d3b |
| institution | DOAJ |
| issn | 0042-4625 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj-art-2fe2a26a9b514c2cab8392db65da2d3b2025-08-20T03:23:31ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252021-06-011801455310.24884/0042-4625-2021-180-1-45-531258High-resolution esophageal manometry in patients with achalasiaA. A. Smirnov0M. M. Kiriltseva1M. E. Luybchenko2L. I. Davletbaeva3A. V. Kochetkov4Pavlov UniversityPavlov UniversityPavlov UniversityPavlov UniversityNikiforov’s Center for Emergency and Radiation MedicineIntroduction. At present, high-resolution esophageal manometry is the «gold standard» for the diagnosis of esophageal achalasia, based on the determination of the integrated relaxation pressure of the lower esophageal sphincter, the value of which in the case of achalasia must exceed 15 mm Hg (MMS System). However, in some patients with clinically and radiologically confirmed achalasia, this value is normal. There is no unified view of the cause of this phenomenon. We assumed that low pressure figures may be affected by incorrect installation of the manometric catheter.Methods and materials. This research included 149 patients (61 by retrospective estimating the patients data and 88 new patients) with achalasia established during the period from January 2017 to March 2020. When it was impossible to localize the lower esophageal sphincter and take correct measurements during high-resolution manometry in new patients, the X-rays or upper endoscopy was performed to control the manometric catheter placement. If its’ placement was incorrect and the integrated relaxation pressure level was lower than 15 mmHg, repeated high-resolution manometry was performed with the over-the-guidewire manometric catheter placing.Results. In 36 patients of both groups (24.2 %), the manometric data did not correspond to esophageal achalasia; in the prospective group, 12 out of the 19 patients had incorrect manometric data due to inability to visualize lower esophageal sphincter. In the prospective group, the manometric catheter was reinstalled by a guidewire, which allowed visualizing the signs of the lower esophageal sphincter in all cases, and in 15 out of 19 patients (79 %), the integrated relaxation pressure of the lower esophageal sphincter was more than 15 mm Hg.Conclusions. In some cases, the over-the-guidewire installing makes it possible to pass catheter through the lower esophageal sphincter correctly, visualize the lower esophageal sphincter during the high-resolution manometry examination and obtain true pressure values.https://www.vestnik-grekova.ru/jour/article/view/1777achalasiahigh-resolution manometryintegrated relaxation pressure of the lower esophageal sphinctermanometric catheter |
| spellingShingle | A. A. Smirnov M. M. Kiriltseva M. E. Luybchenko L. I. Davletbaeva A. V. Kochetkov High-resolution esophageal manometry in patients with achalasia Вестник хирургии имени И.И. Грекова achalasia high-resolution manometry integrated relaxation pressure of the lower esophageal sphincter manometric catheter |
| title | High-resolution esophageal manometry in patients with achalasia |
| title_full | High-resolution esophageal manometry in patients with achalasia |
| title_fullStr | High-resolution esophageal manometry in patients with achalasia |
| title_full_unstemmed | High-resolution esophageal manometry in patients with achalasia |
| title_short | High-resolution esophageal manometry in patients with achalasia |
| title_sort | high resolution esophageal manometry in patients with achalasia |
| topic | achalasia high-resolution manometry integrated relaxation pressure of the lower esophageal sphincter manometric catheter |
| url | https://www.vestnik-grekova.ru/jour/article/view/1777 |
| work_keys_str_mv | AT aasmirnov highresolutionesophagealmanometryinpatientswithachalasia AT mmkiriltseva highresolutionesophagealmanometryinpatientswithachalasia AT meluybchenko highresolutionesophagealmanometryinpatientswithachalasia AT lidavletbaeva highresolutionesophagealmanometryinpatientswithachalasia AT avkochetkov highresolutionesophagealmanometryinpatientswithachalasia |