Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges
Hepatic epithelioid hemangioendothelioma is a rare vascular tumor with variable clinical features, often leading to delayed diagnosis. We report a 40-year-old man presenting with abdominal distention and significant weight loss. Initial evaluations suggested cirrhosis and vascular pathologies, such...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2025-07-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.1193 |
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| author | Beyza Selvi Ali Emre Bardak Arzu Poyanlı Bilger Çavuş |
| author_facet | Beyza Selvi Ali Emre Bardak Arzu Poyanlı Bilger Çavuş |
| author_sort | Beyza Selvi |
| collection | DOAJ |
| description | Hepatic epithelioid hemangioendothelioma is a rare vascular tumor with variable clinical features, often leading to delayed diagnosis. We report a 40-year-old man presenting with abdominal distention and significant weight loss. Initial evaluations suggested cirrhosis and vascular pathologies, such as Budd–Chiari syndrome. Subsequently, liver biopsy confirmed hepatic epithelioid hemangioendothelioma. A positron emission tomography–computed tomography scan showed liver, bone, and possible colon involvement. Despite planning chemotherapy, the patient died before treatment initiation. This case highlights the importance of considering hepatic epithelioid hemangioendothelioma in the differential diagnosis of unexplained multifocal liver lesions, especially in middle-aged adults. |
| format | Article |
| id | doaj-art-2fdadc0c2f644ec4b0f808ba146b1301 |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-2fdadc0c2f644ec4b0f808ba146b13012025-08-20T03:13:30ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-07-014710.7326/aimcc.2024.1193Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic ChallengesBeyza Selvi0Ali Emre Bardak1Arzu Poyanlı2Bilger Çavuş31Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey2St. Elizabeth's Medical Center, Department of Internal Medicine, Boston, Massachusetts3Istanbul University, Istanbul Faculty of Medicine, Department of Radiology, Istanbul, Turkey4Istanbul University, Istanbul Faculty of Medicine, Department of Gastroenterology, Istanbul, TurkeyHepatic epithelioid hemangioendothelioma is a rare vascular tumor with variable clinical features, often leading to delayed diagnosis. We report a 40-year-old man presenting with abdominal distention and significant weight loss. Initial evaluations suggested cirrhosis and vascular pathologies, such as Budd–Chiari syndrome. Subsequently, liver biopsy confirmed hepatic epithelioid hemangioendothelioma. A positron emission tomography–computed tomography scan showed liver, bone, and possible colon involvement. Despite planning chemotherapy, the patient died before treatment initiation. This case highlights the importance of considering hepatic epithelioid hemangioendothelioma in the differential diagnosis of unexplained multifocal liver lesions, especially in middle-aged adults.https://www.acpjournals.org/doi/10.7326/aimcc.2024.1193 |
| spellingShingle | Beyza Selvi Ali Emre Bardak Arzu Poyanlı Bilger Çavuş Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges Annals of Internal Medicine: Clinical Cases |
| title | Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges |
| title_full | Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges |
| title_fullStr | Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges |
| title_full_unstemmed | Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges |
| title_short | Hepatic Epithelioid Hemangioendothelioma: A Case Report Emphasizing Diagnostic Challenges |
| title_sort | hepatic epithelioid hemangioendothelioma a case report emphasizing diagnostic challenges |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2024.1193 |
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