Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris

Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris

ABSTRACT Low‐cost and safe vaccines are needed to fill the vaccine inequity gap for future pandemics. Pichia pastoris is an ideal expression system for recombinant protein production due to its cost‐effective and easy‐to‐scale‐up process. Here, we developed a next‐generation SARS‐CoV2 Omicron BA.1‐b...

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Main Authors: Sibel Kalyoncu, Dogu Sayili, Ayca Zeybek Kuyucu, Hakan Soyturk, Seyda Gullu, Busra Ersayan, Ibrahim Oguzhan Tarman, Mehmet Ender Avci, Olcay Mert, Umut Haskok, Ege Tekin, Huseyin Akinturk, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Ceren Ulker, Bilgi Gungor, Mehmet Inan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Microbial Biotechnology
Subjects:
COVID‐19 vaccine
omicron BA.1
Pichia pastoris
recombinant protein subunit vaccine
SARS‐CoV‐2
Online Access:https://doi.org/10.1111/1751-7915.70077
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https://doi.org/10.1111/1751-7915.70077

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