CAR-T Cells for the Treatment of Central Nervous System Tumours: Known and Emerging Neurotoxicities
The advent of chimeric antigen receptor (CAR)-T cells has recently changed the prognosis of relapsing/refractory diffuse large B-cell lymphomas, showing response rates as high as 60 to 80%. Common toxicities reported in the pivotal clinical trials include the cytokine release syndrome (CRS) and the...
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| Main Authors: | Leonardo Palazzo, Valentina Pieri, Giulia Berzero, Massimo Filippi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-11-01
|
| Series: | Brain Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3425/14/12/1220 |
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