Malaria exposure remodels the plasma proteome of Ghanaian children

Malaria exposure remodels the plasma proteome of Ghanaian children

Abstract Background Malaria, caused by Plasmodium falciparum, remains a major public health burden causing ~ 200 million deaths annually, especially among children. Although the lack of an effective vaccine has hindered malaria elimination, studies have reported on individuals acquiring natural immu...

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Bibliographic Details
Main Authors: Aisha M. Mohammed, Charles Ochieng’ Olwal, Andrea Fossati, Nancy K. Nyakoe, Jacqueline M. Fabius, Martin Gordon, Benjamin J. Polacco, Danielle L. Swaney, Gordon A. Awandare, Nevan J. Krogan, Mehdi Bouhaddou, Yaw Bediako
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Infectious Diseases
Subjects:
Malaria immunity
Plasma proteomics
Antibodies
IGKV3D-20
Complement cascade
C1QA
Online Access:https://doi.org/10.1186/s12879-025-10495-4
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