Mutation status of refractory to imatinib patients with chronic myeloid leukemia

Mutation status of refractory to imatinib patients with chronic myeloid leukemia

Mutation status of 36 chronic myeloid leukemia (CML) patients in chronic phase with primary and secondary imatinib resistance was analyzed. BCR-ABL mutations identified by direct DNA sequencing. BCR-ABL kinase domain mutations were detected in 30.5 % (11 of 36) of those patients. Most of identified...

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Bibliographic Details
Main Authors: E. G. Ovsyannikova, K. D. Kaplanov, T. Yu. Klitochenko, A. V. Misyurin, I. L. Davydkin, L. V. Zaklyakova, E. A. Popov, B. N. Levitan
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
chronic myeloid leukemia
bcr-abl mutations
resistance
imatinib
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/72
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