Diagnostic performance of a doppler radar-based sleep apnoea testing device

Abstract Background Inpatient polysomnography (PSG) is the gold standard for the diagnosis of obstructive sleep apnoea (OSA), however, both complexity and costs limit the availability of this examination. Home sleep apnoea testing devices are a diagnostic alternative in patients with increased risk...

Full description

Saved in:
Bibliographic Details
Main Authors: Jonathan Röcken, Andrei M. Darie, Leticia Grize, Claire Ellen Dexter, Matthias J. Herrmann, Kathleen Jahn, Werner Strobel, Michael Tamm, Daiana Stolz
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-025-03618-9
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850154029608337408
author Jonathan Röcken
Andrei M. Darie
Leticia Grize
Claire Ellen Dexter
Matthias J. Herrmann
Kathleen Jahn
Werner Strobel
Michael Tamm
Daiana Stolz
author_facet Jonathan Röcken
Andrei M. Darie
Leticia Grize
Claire Ellen Dexter
Matthias J. Herrmann
Kathleen Jahn
Werner Strobel
Michael Tamm
Daiana Stolz
author_sort Jonathan Röcken
collection DOAJ
description Abstract Background Inpatient polysomnography (PSG) is the gold standard for the diagnosis of obstructive sleep apnoea (OSA), however, both complexity and costs limit the availability of this examination. Home sleep apnoea testing devices are a diagnostic alternative in patients with increased risk of OSA. We evaluated the diagnostic performance of a Doppler radar technology based, contactless sleep apnoea testing device (CSATD) in a cohort of patients with a clinically increased risk of OSA. Methods Monocentric prospective study. Sleep monitoring with the CSATD SleepizOne + without pulse oximetry (Sleepiz AG, Switzerland) was performed simultaneously with elective inpatient PSG. PSG was analysed blinded to the CSATD results and according to AASM 2012 criteria by certified sleep physicians. The CSATD data were analysed automatically and independently by a dedicated software. Results A total of 102 patients, 60.8% male, with an average age of 55 ± 15 years and body mass index of 30 ± 6 kg/m2 were included in the analysis. The sensitivity and specificity of the CSATD for a PSG apnoea-hypopnoea-index (AHI) of ≥ 5/h were 0.89 (95%CI: 0.83–0.96) and 0.88 (95%CI: 0.73-1.0). The negative and positive predictive values were 0.62 (95%CI: 0.42–0.82) and 0.97 (95%CI: 0.94-1.0). The diagnostic agreement for the diagnosis of OSA (defined as PSG AHI ≥ 5/h) was 89.8% and 100% using a CSATD AHI threshold of ≥ 5/h (n = 79/88) and ≥ 15/h (n = 61/61). However, the concordance was poor in the classification of OSA severity, with 50% (13/26) concordance for mild, 38% (10/26) for moderate, and 76% (25/33) for severe OSA respectively. Conclusion CSATD accurately identifies patients with OSA, particularly using an AHI threshold of ≥ 15/h. However, it performs subpar in disease severity stratification. Clinical trial registration This trial was registered on the International Clinical Trials Registry Platform, ISRCTN45778591.
format Article
id doaj-art-2fb45e2c4f704517b5197ac2e6e263c1
institution OA Journals
issn 1471-2466
language English
publishDate 2025-04-01
publisher BMC
record_format Article
series BMC Pulmonary Medicine
spelling doaj-art-2fb45e2c4f704517b5197ac2e6e263c12025-08-20T02:25:34ZengBMCBMC Pulmonary Medicine1471-24662025-04-012511810.1186/s12890-025-03618-9Diagnostic performance of a doppler radar-based sleep apnoea testing deviceJonathan Röcken0Andrei M. Darie1Leticia Grize2Claire Ellen Dexter3Matthias J. Herrmann4Kathleen Jahn5Werner Strobel6Michael Tamm7Daiana Stolz8Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine, University of FreiburgClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital BaselClinic of Respiratory Medicine, University of FreiburgAbstract Background Inpatient polysomnography (PSG) is the gold standard for the diagnosis of obstructive sleep apnoea (OSA), however, both complexity and costs limit the availability of this examination. Home sleep apnoea testing devices are a diagnostic alternative in patients with increased risk of OSA. We evaluated the diagnostic performance of a Doppler radar technology based, contactless sleep apnoea testing device (CSATD) in a cohort of patients with a clinically increased risk of OSA. Methods Monocentric prospective study. Sleep monitoring with the CSATD SleepizOne + without pulse oximetry (Sleepiz AG, Switzerland) was performed simultaneously with elective inpatient PSG. PSG was analysed blinded to the CSATD results and according to AASM 2012 criteria by certified sleep physicians. The CSATD data were analysed automatically and independently by a dedicated software. Results A total of 102 patients, 60.8% male, with an average age of 55 ± 15 years and body mass index of 30 ± 6 kg/m2 were included in the analysis. The sensitivity and specificity of the CSATD for a PSG apnoea-hypopnoea-index (AHI) of ≥ 5/h were 0.89 (95%CI: 0.83–0.96) and 0.88 (95%CI: 0.73-1.0). The negative and positive predictive values were 0.62 (95%CI: 0.42–0.82) and 0.97 (95%CI: 0.94-1.0). The diagnostic agreement for the diagnosis of OSA (defined as PSG AHI ≥ 5/h) was 89.8% and 100% using a CSATD AHI threshold of ≥ 5/h (n = 79/88) and ≥ 15/h (n = 61/61). However, the concordance was poor in the classification of OSA severity, with 50% (13/26) concordance for mild, 38% (10/26) for moderate, and 76% (25/33) for severe OSA respectively. Conclusion CSATD accurately identifies patients with OSA, particularly using an AHI threshold of ≥ 15/h. However, it performs subpar in disease severity stratification. Clinical trial registration This trial was registered on the International Clinical Trials Registry Platform, ISRCTN45778591.https://doi.org/10.1186/s12890-025-03618-9Home sleep apnoea testingHSATObstructive sleep apnoeaOSASleepizContactless sleep apnoea testing device
spellingShingle Jonathan Röcken
Andrei M. Darie
Leticia Grize
Claire Ellen Dexter
Matthias J. Herrmann
Kathleen Jahn
Werner Strobel
Michael Tamm
Daiana Stolz
Diagnostic performance of a doppler radar-based sleep apnoea testing device
BMC Pulmonary Medicine
Home sleep apnoea testing
HSAT
Obstructive sleep apnoea
OSA
Sleepiz
Contactless sleep apnoea testing device
title Diagnostic performance of a doppler radar-based sleep apnoea testing device
title_full Diagnostic performance of a doppler radar-based sleep apnoea testing device
title_fullStr Diagnostic performance of a doppler radar-based sleep apnoea testing device
title_full_unstemmed Diagnostic performance of a doppler radar-based sleep apnoea testing device
title_short Diagnostic performance of a doppler radar-based sleep apnoea testing device
title_sort diagnostic performance of a doppler radar based sleep apnoea testing device
topic Home sleep apnoea testing
HSAT
Obstructive sleep apnoea
OSA
Sleepiz
Contactless sleep apnoea testing device
url https://doi.org/10.1186/s12890-025-03618-9
work_keys_str_mv AT jonathanrocken diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT andreimdarie diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT leticiagrize diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT claireellendexter diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT matthiasjherrmann diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT kathleenjahn diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT wernerstrobel diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT michaeltamm diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice
AT daianastolz diagnosticperformanceofadopplerradarbasedsleepapnoeatestingdevice