INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID
Smoking is one of the main factors of a wide range of diseases as ischemic heart disease, stroke, chronic obstructive pulmonary disease. To know mechanisms of smoking influence on the course of these diseases might lead to discovery of novel methods of diagnostics and prevention. Recent studies show...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2015-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/286 |
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| author | A. V. Kiseleva A. A. Zharikova A. N. Meshkov |
| author_facet | A. V. Kiseleva A. A. Zharikova A. N. Meshkov |
| author_sort | A. V. Kiseleva |
| collection | DOAJ |
| description | Smoking is one of the main factors of a wide range of diseases as ischemic heart disease, stroke, chronic obstructive pulmonary disease. To know mechanisms of smoking influence on the course of these diseases might lead to discovery of novel methods of diagnostics and prevention. Recent studies showed the impact of smoking on epigenetic mechanisms of heredity, particularly on the status of DNA methylizing. Current review focuses on the analysis of smoking influence of DNA methylizing. There are >60 genes described, methylizing of which is related to smoking. There is relation of methylizing level of genes AHRR, MMP25, PTGDS, WWC3, SASH1 not only with smoking but atherosclerosis. |
| format | Article |
| id | doaj-art-2fb197f16b21415d87d6ed582cd5fb8e |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2015-12-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-2fb197f16b21415d87d6ed582cd5fb8e2025-08-20T02:59:52Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252015-12-01146737710.15829/1728-8800-2015-6-73-77281INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACIDA. V. Kiseleva0A. A. Zharikova1A. N. Meshkov2National Research Center for Preventive Medicine of the Ministry of Health, MoscowNational Research Center for Preventive Medicine of the Ministry of Health, MoscowNational Research Center for Preventive Medicine of the Ministry of Health, MoscowSmoking is one of the main factors of a wide range of diseases as ischemic heart disease, stroke, chronic obstructive pulmonary disease. To know mechanisms of smoking influence on the course of these diseases might lead to discovery of novel methods of diagnostics and prevention. Recent studies showed the impact of smoking on epigenetic mechanisms of heredity, particularly on the status of DNA methylizing. Current review focuses on the analysis of smoking influence of DNA methylizing. There are >60 genes described, methylizing of which is related to smoking. There is relation of methylizing level of genes AHRR, MMP25, PTGDS, WWC3, SASH1 not only with smoking but atherosclerosis.https://cardiovascular.elpub.ru/jour/article/view/286smokingmethylizingewasepigenetics |
| spellingShingle | A. V. Kiseleva A. A. Zharikova A. N. Meshkov INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID Кардиоваскулярная терапия и профилактика smoking methylizing ewas epigenetics |
| title | INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID |
| title_full | INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID |
| title_fullStr | INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID |
| title_full_unstemmed | INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID |
| title_short | INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID |
| title_sort | influence of smoking on the methylizing status of desoxyribonucleic acid |
| topic | smoking methylizing ewas epigenetics |
| url | https://cardiovascular.elpub.ru/jour/article/view/286 |
| work_keys_str_mv | AT avkiseleva influenceofsmokingonthemethylizingstatusofdesoxyribonucleicacid AT aazharikova influenceofsmokingonthemethylizingstatusofdesoxyribonucleicacid AT anmeshkov influenceofsmokingonthemethylizingstatusofdesoxyribonucleicacid |